Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT1 | P54687 | 5/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 3/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.30 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22151194 | 0.75 | ALOX5 (0.46) | KDM4EMEN1ALDH1A1KMT2AALOX5 | |
| SCHEMBL18848559 | 0.74 | ALOX5 (0.36) | HSP90AA1HSP90AB1ALOX5 | |
| SCHEMBL20121357 | 0.72 | NPC1 (0.35) | BCAT1TTRHSP90AA1HSP90AB1NPC1 | |
| SCHEMBL25547131 | 0.70 | NPC1 (0.38) | BCAT1TTRNPC1RAB9AIDO1 | |
| SCHEMBL24021510 | 0.70 | NPC1 (0.31) | NPC1RAB9A | |
| SCHEMBL18809976 | 0.70 | ALOX5 (0.38) | BCAT1ALOX5 | |
| SCHEMBL20273174 | 0.70 | NPC1 (0.42) | BCAT1TTRNPC1RAB9AIDO1 | |
| SCHEMBL24370038 | 0.69 | HPGD (0.44) | HSP90AA1HSP90AB1NPC1RAB9AAHR | |
| SCHEMBL25098398 | 0.69 | HPGD (0.44) | HSP90AA1HSP90AB1NPC1RAB9AAHR | |
| SCHEMBL24496648 | 0.69 | PLA2G2A (0.35) | BCAT1TTRNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9087997-B2 | Aromatic amine derivative and organic electroluminescence device | IDEMITSU KOSAN CO., LTD. (JP) | 2015-07-21 | — | — | US | disclosed |
| US-20140061630-A1 | AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2014-03-06 | — | — | US | disclosed |