Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 7/20 | 0.40 |
| ▸ | MAOA | P21397 | 5/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 4/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21996640 | 0.87 | ABCB1 (0.48) | ABCB1GPR119SRCBACE1BACE2 | |
| SCHEMBL7327353 | 0.87 | ABCB1 (0.58) | ABCB1GPR119BDKRB2SRC | |
| SCHEMBL475540 | 0.87 | ABCB1 (0.58) | ABCB1GPR119BDKRB2SRC | |
| SCHEMBL3855580 | 0.87 | ABCB1 (0.58) | ABCB1GPR119BDKRB2SRC | |
| SCHEMBL71548 | 0.87 | ABCB1 (0.58) | ABCB1GPR119BDKRB2SRC | |
| SCHEMBL28995867 | 0.87 | ABCB1 (0.58) | ABCB1GPR119BDKRB2SRC | |
| SCHEMBL30421047 | 0.87 | ABCB1 (0.58) | ABCB1GPR119BDKRB2SRC | |
| SCHEMBL21996445 | 0.84 | ABCB1 (0.43) | ABCB1GPR119MAOBBDKRB2SRC | |
| SCHEMBL15499687 | 0.84 | ABCB1 (0.42) | ABCB1GPR119CARM1PRMT6PRMT8 | |
| SCHEMBL15499688 | 0.84 | ABCB1 (0.42) | ABCB1MAOBMAOABDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140066635-A1 | Thiophene-2-carboximidamide Based Selective Neuronal Nitric Oxide Inhibitors | NORTHWESTERN UNIVERSITY (US) | 2014-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140066635-A1 | Thiophene-2-carboximidamide Based Selective Neuronal Nitric Oxide Inhibitors | NOS2, NOS1, NOS3 | ABCB1 2151/4885GPR119 518/4885CARM1 1966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.