Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.33 |
| ▸ | LSS | P48449 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10081278 | 0.93 | ALDH1A1 (0.43) | ALDH1A1TSHRKDM4ESMN1; SMN2SPHK1 | |
| SCHEMBL14577269 | 0.85 | CA12 (0.38) | ALDH1A1TSHRKDM4ESMN1; SMN2SPHK1 | |
| SCHEMBL9629070 | 0.83 | HTT (0.35) | ALDH1A1TSHRKDM4ESMN1; SMN2SPHK1 | |
| SCHEMBL29651757 | 0.82 | ALDH1A1 (0.36) | ALDH1A1TSHRKDM4ESMN1; SMN2SPHK1 | |
| SCHEMBL29651760 | 0.82 | ALDH1A1 (0.36) | ALDH1A1TSHRKDM4ESMN1; SMN2SPHK1 | |
| SCHEMBL15182727 | 0.81 | CA12 (0.44) | ALDH1A1TSHRKDM4ESMN1; SMN2PIK3CD | |
| SCHEMBL15510982 | 0.80 | SPHK1 (0.37) | SPHK1SPHK2PIK3CD | |
| SCHEMBL13169202 | 0.80 | ALDH1A1 (0.31) | ALDH1A1TSHRKDM4ESMN1; SMN2SPHK1 | |
| SCHEMBL15182743 | 0.79 | ALDH1A1 (0.38) | ALDH1A1TSHRKDM4ESMN1; SMN2HRH3 | |
| SCHEMBL7527905 | 0.79 | USP2 (0.44) | ALDH1A1TSHRKDM4ESMN1; SMN2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11279735-B2 | Cyclic peptide antibiotics | GENENTECH, INC. (US) | 2022-03-22 | — | — | US | disclosed |
| US-20200331968-A1 | CYCLIC PEPTIDE ANTIBIOTICS | GENENTECH, INC. (US) | 2020-10-22 | — | — | US | disclosed |
| WO-2020185999-A1 | CYCLIC PEPTIDE ANTIBIOTICS | GENENTECH, INC. (US) | 2020-09-17 | — | — | WO | disclosed |
| WO-2019052545-A1 | CYCLIC PEPTIDE ANTIBIOTICS | F. HOFFMANN-LA ROCHE AG (CH) | 2019-03-21 | — | — | WO | disclosed |
| EP-2708529-B1 | METHOD FOR MANUFACTURING PARTICLES | SUMITOMO CHEMICAL CO (JP) | 2018-04-04 | — | — | EP | disclosed |
| US-9796831-B2 | Process for producing particles | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-10-24 | — | — | US | disclosed |
| CN-103974929-B | The manufacture method of the halogen acid salt of haloalkylamine | 住友化学株式会社 | 2016-08-24 | — | — | CN | disclosed |
| CN-103534236-B | Method for producing granules | 住友化学株式会社 | 2016-08-17 | — | — | CN | disclosed |
| CN-103974929-A | Method for producing hydrohalic acid salt of halogenated alkyl amine | SUMITOMO CHEMICAL CO | 2014-08-06 | — | — | CN | disclosed |
| EP-2708529-A1 | METHOD FOR MANUFACTURING PARTICLES | Sumitomo Chemical Company Limited (JP) | 2014-03-19 | — | — | EP | disclosed |
| US-20140065337-A1 | PROCESS FOR PRODUCING PARTICLES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-03-06 | — | — | US | disclosed |
| CN-103534236-A | Method for producing granules | SUMITOMO CHEMICAL CO | 2014-01-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200331968-A1 | CYCLIC PEPTIDE ANTIBIOTICS | NPPA, LNPEP, CLPP | ALDH1A1 4279/4885TSHR 2876/4885KDM4E 3065/4885 |
| US-11279735-B2 | Cyclic peptide antibiotics | NPPA, LNPEP, CLPP | ALDH1A1 4279/4885TSHR 2876/4885KDM4E 3065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.