SCHEMBL1551395

SCHEMBL1551395

CCC=CCC=CCC=CCC=CCC=CCCCCS

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.52
CYP19A1 P11511 4/20 0.52
F7 P08709 3/20 0.52
F3 P13726 3/20 0.52
MAPT P10636 3/20 0.52
OXER1 Q8TDS5 3/20 0.52
PPARG P37231 3/20 0.52
PTGS1 P23219 2/20 0.52
KMT2A Q03164 2/20 0.52
PPARD Q03181 2/20 0.52
PPARA Q07869 2/20 0.52
CYP3A4 P08684 2/20 0.52
ALOX15 P16050 2/20 0.52
HSD17B10 Q99714 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
NR1I2 O75469 2/20 0.52
PTGS2 P35354 2/20 0.52
FFAR1 O14842 2/20 0.52
KDM4E B2RXH2 1/20 0.52
MEN1 O00255 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3803268 1.00 ALDH1A1 (0.52) ALDH1A1CYP19A1F7F3MAPT
SCHEMBL3803270 1.00 ALDH1A1 (0.52) ALDH1A1CYP19A1F7F3MAPT
SCHEMBL1551393 1.00 ALDH1A1 (0.52) ALDH1A1CYP19A1F7F3MAPT
SCHEMBL19686813 1.00 ALDH1A1 (0.52) ALDH1A1CYP19A1F7F3MAPT
SCHEMBL24651305 0.98 ALDH1A1 (0.55) ALDH1A1CYP19A1F7F3MAPT
SCHEMBL814686 0.98 ALDH1A1 (0.55) ALDH1A1CYP19A1F7F3MAPT
SCHEMBL21313309 0.90 ALDH1A1 (0.45) ALDH1A1CYP19A1F7F3MAPT
SCHEMBL14617944 0.85
SCHEMBL4465662 0.85 ALDH1A1 (0.65) ALDH1A1CYP19A1F7F3MAPT
SCHEMBL4465665 0.85 ALDH1A1 (0.65) ALDH1A1CYP19A1F7F3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12465580-B2 Substituted fatty acids for treating non-alcoholic steatohepatitis BASF AS (NO) 2025-11-11 US disclosed
EP-3288550-B1 STRUCTURALLY ENHANCED FATTY ACIDS CONTAINING SULPHUR FOR THEIR USE IN TREATING NON-ALCOHOLIC STEATOHEPATITIS BASF AS (NO) 2024-06-05 EP disclosed
US-20240156760-A1 SUBSTITUTED FATTY ACIDS FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS BASF AS (NO) 2024-05-16 US disclosed
US-11911354-B2 Substituted fatty acids for treating non-alcoholic steatohepatitis BASF (NO) 2024-02-27 US disclosed
US-11911354-B2 Substituted fatty acids for treating non-alcoholic steatohepatitis BASF (NO) 2024-02-27 US disclosed
US-11911354-B2 Substituted fatty acids for treating non-alcoholic steatohepatitis BASF (NO) 2024-02-27 US disclosed
US-20220280459-A1 SUBSTITUTED FATTY ACIDS FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS BASF AS (NO) 2022-09-08 US disclosed
US-11234948-B2 Substituted fatty acids for treating non-alcoholic steatohepatitis BASF AS (NO) 2022-02-01 US disclosed
US-11234948-B2 Substituted fatty acids for treating non-alcoholic steatohepatitis BASF AS (NO) 2022-02-01 US disclosed
US-10722481-B2 Substituted fatty acids for treating non-alcoholic steatohepatitis BASF AS (NO) 2020-07-28 US disclosed
US-20110190395-A1 NOVEL SULPHUR CONTAINING LIPIDS FOR USE AS FOOD SUPPLEMENT OR AS MEDICAMENT PRONOVA BIOPHARMA NORGE AS (NO) 2011-08-04 US disclosed
WO-2011089529-A1 SALICYLATE FATTY ACID DERIVATIVES PRONOVA BIOPHARMA NORGE AS (NO) 2011-07-28 WO disclosed
EP-2313090-A1 NOVEL SULPHUR CONTAINING LIPIDS FOR USE AS FOOD SUPPLEMENT OR AS MEDICAMENT Pronova BioPharma Norge AS (NO) 2011-04-27 EP disclosed
US-20100280109-A1 LIPID COMPOUNDS FOR USE IN COSMETIC PRODUCTS, AS FOOD SUPPLEMENT OR AS A MEDICAMENT PRONOVA BIOPHARMA NORGE AS (NO) 2010-11-04 US disclosed
US-20100280109-A1 LIPID COMPOUNDS FOR USE IN COSMETIC PRODUCTS, AS FOOD SUPPLEMENT OR AS A MEDICAMENT PRONOVA BIOPHARMA NORGE AS (NO) 2010-11-04 US disclosed
US-20100280109-A1 LIPID COMPOUNDS FOR USE IN COSMETIC PRODUCTS, AS FOOD SUPPLEMENT OR AS A MEDICAMENT PRONOVA BIOPHARMA NORGE AS (NO) 2010-11-04 US disclosed
EP-2147910-A1 Novel lipid compounds Pronova BioPharma Norge AS (NO) 2010-01-27 EP disclosed
WO-2010008299-A1 NOVEL SULPHUR CONTAINING LIPIDS FOR USE AS FOOD SUPPLEMENT OR AS MEDICAMENT PRONOVA BIOPHARMA NORGE AS (NO) 2010-01-21 WO disclosed
WO-2010008299-A1 NOVEL SULPHUR CONTAINING LIPIDS FOR USE AS FOOD SUPPLEMENT OR AS MEDICAMENT PRONOVA BIOPHARMA NORGE AS (NO) 2010-01-21 WO disclosed
WO-2009061208-A1 LIPID COMPOUNDS FOR USE IN COSMETIC PRODUCTS, AS FOOD SUPPLEMENT OR AS A MEDICAMENT PRONOVA BIOPHARMA NORGE AS (NO) 2009-05-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12465580-B2 Substituted fatty acids for treating non-alcoholic steatohepatitis SLC10A1, LIPC, FABP1 ALDH1A1 443/4885CYP19A1 689/4885F7 1250/4885
US-20240156760-A1 SUBSTITUTED FATTY ACIDS FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS SLC10A1, LIPC, FABP1 ALDH1A1 443/4885CYP19A1 689/4885F7 1250/4885
US-11234948-B2 Substituted fatty acids for treating non-alcoholic steatohepatitis SLC10A1, LIPC, FABP1 ALDH1A1 443/4885CYP19A1 689/4885F7 1250/4885
US-10722481-B2 Substituted fatty acids for treating non-alcoholic steatohepatitis SLC10A1, LIPC, FABP1 ALDH1A1 443/4885CYP19A1 689/4885F7 1250/4885
US-20110190395-A1 NOVEL SULPHUR CONTAINING LIPIDS FOR USE AS FOOD SUPPLEMENT OR AS MEDICAMENT SGMS2, SGMS1, ACSS2 ALDH1A1 514/4885CYP19A1 2818/4885F7 1599/4885
US-20220280459-A1 SUBSTITUTED FATTY ACIDS FOR TREATING NON-ALCOHOLIC STEATOHEPATITIS SLC10A1, LIPC, FABP1 ALDH1A1 443/4885CYP19A1 689/4885F7 1250/4885
US-11911354-B2 Substituted fatty acids for treating non-alcoholic steatohepatitis SLC10A1, LIPC, FABP1 ALDH1A1 443/4885CYP19A1 689/4885F7 1250/4885
US-20100280109-A1 LIPID COMPOUNDS FOR USE IN COSMETIC PRODUCTS, AS FOOD SUPPLEMENT OR AS A MEDICAMENT SGMS1, SGMS2, C1S ALDH1A1 327/4885CYP19A1 418/4885F7 347/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.