SCHEMBL15516477

SCHEMBL15516477

C[C](C)c1cc(F)cc(Cl)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 1/20 0.41
TAS1R1 Q7RTX1 1/20 0.41
TAS1R2 Q8TE23 1/20 0.41
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
GPR139 Q6DWJ6 1/20 0.36
RAPGEF4 Q8WZA2 1/20 0.36
TPMT P51580 1/20 0.36
GPBAR1 Q8TDU6 1/20 0.33
IDO1 P14902 1/20 0.33
CACNA1H O95180 4/20 0.32
CACNA1G O43497 1/20 0.32
CACNA1I Q9P0X4 1/20 0.32
TSHR P16473 1/20 0.32
CSF1R P07333 1/20 0.32
HCAR1 Q9BXC0 2/20 0.31
EPAS1 Q99814 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16956770 0.84 TAS1R3 (0.41) TAS1R3TAS1R1TAS1R2CES2CES1
SCHEMBL1160981 0.82 TAS1R3 (0.46) TAS1R3TAS1R1TAS1R2CES2CES1
SCHEMBL3073672 0.82 TSHR (0.50) TPMTTSHRHCAR1
SCHEMBL16959008 0.76 TAS1R3 (0.36) TAS1R3TAS1R1TAS1R2CES2CES1
SCHEMBL5223999 0.74 CES2 (0.46) TAS1R3TAS1R1TAS1R2CES2CES1
SCHEMBL20560604 0.74 MAOB (0.40) TAS1R3TAS1R1TAS1R2CES2CES1
SCHEMBL29558481 0.74 CES2 (0.46) TAS1R3TAS1R1TAS1R2CES2CES1
SCHEMBL572200 0.74 TPMT (0.70) TAS1R3TAS1R1TAS1R2CES2CES1
SCHEMBL29454778 0.74 TPMT (0.70) TAS1R3TAS1R1TAS1R2CES2CES1
SCHEMBL16961662 0.74 GPR139 (0.39) TAS1R3TAS1R1TAS1R2CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2887802-A2 METHODS OF SOIL PEST CONTROL Syngenta Participations AG (CH) 2015-07-01 EP disclosed
WO-2014029708-A1 METHODS OF CONTROLLING INSECTS SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 WO disclosed
WO-2014029707-A1 METHODS OF CONTROLLING INSECTS SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 WO disclosed
WO-2014029706-A2 METHODS OF CONTROLLING INSECTS SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 WO disclosed
WO-2014029710-A2 METHODS OF SOIL PEST CONTROL SYNGENTA PARTICIPATIONS AG (CH) 2014-02-27 WO disclosed
WO-2014019609-A1 METHODS OF PEST CONTROL IN SOYBEAN SYNGENTA PARTICIPATIONS AG (CH) 2014-02-06 WO disclosed