SCHEMBL15516652

SCHEMBL15516652

CC(=CCC(=O)c1ccc(C#N)cc1)c1ccc(F)cc1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 2/20 0.49
GSK3B P49841 1/20 0.47
EPHX2 P34913 3/20 0.43
ALDH1A1 P00352 1/20 0.42
MAPT P10636 1/20 0.42
VNN1 O95497 1/20 0.41
RAB9A P51151 2/20 0.41
CYP19A1 P11511 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
PTPN1 P18031 1/20 0.40
NPC1 O15118 1/20 0.40
HTR7 P34969 1/20 0.40
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
CYP2J2 P51589 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15509295 1.00 NSD2 (0.49) NSD2GSK3BEPHX2ALDH1A1MAPT
SCHEMBL15516651 1.00 NSD2 (0.49) NSD2GSK3BEPHX2ALDH1A1MAPT
SCHEMBL19367865 0.78 GSK3B (0.59) NSD2GSK3BEPHX2MAPTVNN1
SCHEMBL9756773 0.76 NPC1 (0.52) ALDH1A1MAPTRAB9ACA1CA2
SCHEMBL28365872 0.75 CES2 (0.43) ALDH1A1MAPTRAB9ACA1CA2
SCHEMBL2556035 0.73 GSK3B (0.61) GSK3BALDH1A1MAPTRAB9ACA1
SCHEMBL7935350 0.72 VNN1 (0.60) NSD2GSK3BEPHX2ALDH1A1VNN1
SCHEMBL8110686 0.72 NSD2 (0.56) NSD2GSK3BEPHX2VNN1RAB9A
SCHEMBL20837775 0.71 SLC6A3 (0.48) EPHX2ALDH1A1MAPT
SCHEMBL10996566 0.71 MAPT (0.50) GSK3BALDH1A1MAPTRAB9APTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014037963-A1 A PROCESS FOR THE SYNTHESIS OF β, ƴ UNSATURATED KETONES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2014-03-13 WO claimed
WO-2014037963-A1 A PROCESS FOR THE SYNTHESIS OF β, ƴ UNSATURATED KETONES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2014-03-13 WO disclosed