Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | TTK | P33981 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8320853 | 0.85 | NAMPT (0.40) | NAMPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL2892633 | 0.83 | ALDH1A1 (0.39) | ELANEMEN1KMT2AKDM4ELMNA | |
| SCHEMBL21324100 | 0.83 | ALDH1A1 (0.50) | ELANEMEN1KMT2AKDM4ELMNA | |
| SCHEMBL31647254 | 0.79 | CCNA2 (0.46) | ELANEMEN1KMT2AKDM4ELMNA | |
| SCHEMBL29789796 | 0.75 | KDM4E (0.60) | ELANEKDM4ELMNAADORA3PKM | |
| SCHEMBL260569 | 0.75 | KDM4E (0.60) | ELANEKDM4ELMNAADORA3PKM | |
| SCHEMBL590272 | 0.74 | KDR (0.43) | NAMPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL12536276 | 0.73 | MAPK13 (0.42) | NAMPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL28442923 | 0.73 | LIMK1 (0.42) | MEN1KMT2AKDM4ELMNAADORA3 | |
| SCHEMBL28434877 | 0.72 | SLC9A1 (0.41) | MEN1KMT2AKDM4ELMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551864-A | Substituted tricyclic amides, analogs thereof, and methods of using the same | 爱彼特生物制药公司 | 2022-12-30 | — | — | CN | claimed |
| CN-106660996-B | 2, 5-substituted pyrimidines as PDE4 inhibitors | 格吕伦塔尔有限公司 | 2020-10-16 | — | — | CN | claimed |
| CN-115551864-A | Substituted tricyclic amides, analogs thereof, and methods of using the same | 爱彼特生物制药公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-106660996-B | 2, 5-substituted pyrimidines as PDE4 inhibitors | 格吕伦塔尔有限公司 | 2020-10-16 | — | — | CN | disclosed |
| EP-2890693-A1 | PYRAZOLE DERIVATIVES AS P38 MAP INHIBITORS | Respivert Limited (GB) | 2015-07-08 | — | — | EP | disclosed |
| WO-2014033448-A1 | PYRAZOLE DERIVATIVES AS P38 MAP INHIBITORS | RESPIVERT LIMTED (GB) | 2014-03-06 | — | — | WO | disclosed |