Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11706050 | 0.83 | CA9 (0.41) | ALDH1A1MAPTL3MBTL1CA9CA12 | |
| SCHEMBL10100512 | 0.77 | TERT (0.46) | KMT2AALDH1A1MEN1MAPTHSD17B10 | |
| SCHEMBL29643230 | 0.77 | ALDH1A1 (0.49) | KMT2AALDH1A1MAPTHSD17B10ALOX15 | |
| SCHEMBL83222 | 0.77 | ALDH1A1 (0.49) | KMT2AALDH1A1MAPTHSD17B10ALOX15 | |
| SCHEMBL6193007 | 0.77 | ALDH1A1 (0.49) | KMT2AALDH1A1MAPTHSD17B10ALOX15 | |
| SCHEMBL1001751 | 0.75 | POLB (0.50) | KMT2AALDH1A1MAPTHSD17B10ALOX15 | |
| SCHEMBL30595375 | 0.71 | POLB (0.50) | KMT2AALDH1A1MAPTHSD17B10ALOX15 | |
| SCHEMBL2616778 | 0.71 | APP (0.67) | KMT2AALDH1A1MEN1MAPTHSD17B10 | |
| SCHEMBL11948126 | 0.71 | ALDH1A1 (0.41) | KMT2AALDH1A1MEN1MAPTHSD17B10 | |
| SCHEMBL2665475 | 0.71 | MAOA (0.50) | ALDH1A1HSD17B10CA9CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2885302-B1 | PROCESS FOR THE PREPARATION OF DIPEPTIDYLPEPTIDASE INHIBITORS | GLENMARK PHARMACEUTICALS LTD (IN) | 2018-03-07 | — | — | EP | disclosed |
| US-9593119-B2 | Process for the preparation of dipeptidylpeptidase inhibitors | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2017-03-14 | — | — | US | disclosed |
| US-20160272642-A1 | PROCESS FOR THE PREPARATION OF DIPEPTIDYLPEPTIDASE INHIBITORS | GLENMARK LIFE SCIENCES LIMITED (IN) | 2016-09-22 | — | — | US | disclosed |
| US-9353114-B2 | Process for the preparation of dipeptidylpeptidase inhibitors | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2016-05-31 | — | — | US | disclosed |
| US-20150239887-A1 | PROCESS FOR THE PREPARATION OF DIPEPTIDYLPEPTIDASE INHIBITORS | GLENMARK GENERICS LIMITED (IN) | 2015-08-27 | — | — | US | disclosed |
| EP-2885302-A2 | PROCESS FOR THE PREPARATION OF DIPEPTIDYLPEPTIDASE INHIBITORS | Glenmark Pharmaceuticals Limited (IN) | 2015-06-24 | — | — | EP | disclosed |
| WO-2014033746-A2 | PROCESS FOR THE PREPARATION OF DIPEPTIDYLPEPTIDASE INHIBITORS | GLENMARK PHARMACEUTICALS LIMITED; GLENMARK GENERICS LIMITED (IN) | 2014-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239887-A1 | PROCESS FOR THE PREPARATION OF DIPEPTIDYLPEPTIDASE INHIBITORS | DPP4, DPP9, DPP3 | KMT2A 1054/4885ALDH1A1 590/4885MEN1 4176/4885 |
| US-20160272642-A1 | PROCESS FOR THE PREPARATION OF DIPEPTIDYLPEPTIDASE INHIBITORS | DPP9, DPP4, DPP7 | KMT2A 1189/4885ALDH1A1 681/4885MEN1 3730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.