Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | STAT3 | P40763 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28485531 | 0.78 | L3MBTL1 (0.64) | L3MBTL1HTTSMN1; SMN2STAT3LMNA | |
| SCHEMBL4785237 | 0.76 | PPARG (0.45) | L3MBTL1HTTSMN1; SMN2STAT3LMNA | |
| SCHEMBL1551850 | 0.75 | L3MBTL1 (0.55) | L3MBTL1HTTSMN1; SMN2STAT3LMNA | |
| SCHEMBL31574614 | 0.75 | L3MBTL1 (0.55) | L3MBTL1HTTSMN1; SMN2STAT3LMNA | |
| SCHEMBL30986715 | 0.75 | L3MBTL1 (0.55) | L3MBTL1HTTSMN1; SMN2STAT3LMNA | |
| SCHEMBL4740388 | 0.71 | ALDH1A1 (0.69) | L3MBTL1HTTSMN1; SMN2STAT3LMNA | |
| SCHEMBL4740398 | 0.71 | HTT (0.40) | L3MBTL1HTTSMN1; SMN2STAT3LMNA | |
| SCHEMBL372693 | 0.71 | EGFR (0.49) | L3MBTL1HTTSMN1; SMN2STAT3LMNA | |
| SCHEMBL26812621 | 0.69 | L3MBTL1 (1.00) | L3MBTL1HTTSMN1; SMN2STAT3LMNA | |
| SCHEMBL8588718 | 0.69 | HTT (1.00) | L3MBTL1HTTSMN1; SMN2STAT3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008081096-A2 | QUINOLINYL DERIVATIVES, METHOD FOR PREPARING SAME, PHARMACEUTIC COMPOSITIONS CONTAINING SAME, AND USE THEREOF AS HYPOGLYCEMIANT AND HYPOLIPEMIANT AGENTS | LES LABORATOIRES SERVIER (FR) | 2008-07-10 | — | — | WO | disclosed |