Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10586950 | 0.77 | LMNA (0.47) | LMNA | |
| Hydrochloric Acid SCHEMBL444580 | 0.77 | LMNA (0.47) | LMNA | |
| Hydrochloric Acid SCHEMBL15518693 | 0.76 | LMNA (0.31) | LMNA | |
| Iodide SCHEMBL21931200 | 0.76 | LMNA (0.46) | LMNA | |
| Hydrochloric Acid SCHEMBL444579 | 0.75 | LMNA (0.36) | LMNA | |
| Hydrochloric Acid SCHEMBL9078570 | 0.75 | LMNA (0.45) | LMNA | |
| Hydrochloric Acid SCHEMBL15518694 | 0.73 | LMNA (0.41) | LMNA | |
| Bromide SCHEMBL21931169 | 0.71 | LMNA (0.48) | LMNA | |
| Hydrochloric Acid SCHEMBL131919 | 0.70 | LMNA (0.46) | LMNA | |
| SCHEMBL5708594 | 0.69 | TSHR (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9304427-B2 | Carrier for developing an electrostatic latent image, developer and image forming apparatus | RICOH COMPANY, LTD. (JP) | 2016-04-05 | — | — | US | disclosed |
| US-20140072910-A1 | CARRIER FOR DEVELOPING AN ELECTROSTATIC LATENT IMAGE, DEVELOPER AND IMAGE FORMING APPARATUS | RICOH COMPANY, LTD. (JP) | 2014-03-13 | — | — | US | disclosed |