Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 3/20 | 0.35 |
| ▸ | CHRM3 known ✓ | P20309 | 3/20 | 0.35 |
| ▸ | CHRM2 known ✓ | P08172 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10586950 | 1.00 | LMNA (0.47) | LMNATSHRTHRBCHRM5CHRM1 | |
| Iodide SCHEMBL21931200 | 0.99 | LMNA (0.46) | LMNATSHRTHRBCHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL9078570 | 0.97 | LMNA (0.45) | LMNATSHRTHRBCHRM5CHRM1 | |
| Bromide SCHEMBL21931169 | 0.93 | LMNA (0.48) | LMNATSHRTHRBCHRM5CHRM1 | |
| Methacrylic Acid SCHEMBL5068534 | 0.87 | LMNA (0.37) | LMNATSHRTHRB | |
| SCHEMBL12660490 | 0.86 | TSHR (0.40) | LMNATSHRTHRBCHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL5198223 | 0.86 | THRB (0.44) | LMNATSHRTHRBCHRM5CHRM1 | |
| Hydrochloric Acid SCHEMBL28476082 | 0.85 | TSHR (0.44) | LMNATSHRTHRBCHRM5CHRM1 | |
| Hydrogen Sulfide SCHEMBL329768 | 0.84 | TSHR (0.53) | LMNATSHRTHRBPOLBAPEX1 | |
| SCHEMBL17201482 | 0.84 | TSHR (0.53) | LMNATSHRTHRBPOLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637617-B2 | Soil stabilizing compositions | ZYDEX INC. (US) | 2026-05-26 | — | — | US | claimed |
| US-20240352315-A1 | METHODS AND COMPOSITIONS FOR ENHANCED DISPERSION OF PHOSPHOR IN A POLYMERIC MATRIX | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2024-10-24 | — | — | US | claimed |
| US-20240010511-A1 | METHODS AND COMPOSITIONS FOR SYNTHESIS OF PHOSPHOR AND ITS INCORPORATION IN A POLYMER MATRIX FOR LIGHT CONVERSION | SOLGRO, INC. (US) | 2024-01-11 | — | — | US | claimed |
| CN-117317242-A | Flexible metal glass fiber cloth lithium ion battery current collector and preparation method thereof | 重庆市紫建新能源有限公司 | 2023-12-29 | — | — | CN | claimed |
| CN-117038999-A | High-safety porous polymer composite current collector and lithium ion battery | 重庆市紫建新能源有限公司 | 2023-11-10 | — | — | CN | claimed |
| CN-115386122-B | High-corrosion-resistance plastic pipe for ship interior and preparation method thereof | 靖江市海鸿塑胶科技有限公司 | 2023-06-06 | — | — | CN | claimed |
| CN-115368737-B | Masterbatch composition, organic silicon polymer material, and preparation method and application thereof | 广州市瑞合新材料科技有限公司 | 2023-05-02 | — | — | CN | claimed |
| US-20220017778-A1 | Methods of Treating Inorganic Surfaces | ZYDEX, INC. | 2022-01-20 | — | — | US | claimed |
| US-20220017823-A1 | SOIL STABILIZING COMPOSITIONS | ZYDEX, INC. | 2022-01-20 | — | — | US | claimed |
| WO-2020142419-A1 | SOIL STABILIZING COMPOSITIONS | ZYDEX INC. (US) | 2020-07-09 | — | — | WO | claimed |
| US-20020123592-A1 | Organic-inorganic hybrids surface adhesion promoter | ZENASTRA PHOTONICS INC. | 2002-09-05 | — | — | US | claimed |
| US-RE34675-E | Silane coupler, di-trialkoxysilane crosslinker, solvent | DOW CORNING CORPORATION (US) | 1994-07-26 | — | — | US | claimed |
| US-5300327-A | Applying mixture of petroleum and syntehtic hydrocarbon wax blend, aqueous silicone resin emulsion | DOW CORNING CORPORATION (US) | 1994-04-05 | — | — | US | claimed |
| US-5110684-A | Masonry water repellent | DOW CORNING CORPORATION (US) | 1992-05-05 | — | — | US | claimed |
| US-5073195-A | Water soluble silane coupling agent and an alkyltrialkoxysilane; protective coatings for wood, masonry and construction materials | DOW CORNING CORPORATION (US) | 1991-12-17 | — | — | US | claimed |
| US-5051129-A | Silane coupler for waterproofing masonry | DOW CORNING CORPORATION (US) | 1991-09-24 | — | — | US | claimed |
| US-4912239-A | Using a hydroxylamine compound | DOW CORNING CORPORATION (US) | 1990-03-27 | — | — | US | claimed |
| US-4798889-A | HYDROXYLAMINE, POLYMERIZATION INHIBITION | DOW CORNING CORPORATION (US) | 1989-01-17 | — | — | US | claimed |
| EP-0255227-A2 | Coupling agent compositions | DOW CORNING CORPORATION (US) | 1988-02-03 | — | — | EP | claimed |
| US-4689085-A | A MIXTURE OF A BIS(TRIALKOXYSILANE) AND A MONO (TRIALKOXYSILANE; PRIMERS FOR LAMINATES AND COMPOSITES; ADHESION | DOW CORNING CORPORATION (US) | 1987-08-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12637617-B2 | Soil stabilizing compositions | HAO2, H1-0, ARG1 | CHRM1 108/4885CHRM3 486/4885CHRM2 83/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.