Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD51 | Q06609 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1119956 | 0.81 | HPGD (0.39) | ALOX15MAPK1TP53HSD17B10SMN1; SMN2 | |
| SCHEMBL23869549 | 0.81 | ATM (0.33) | MAPK1CRHBPATMCRHR2MAPT | |
| SCHEMBL18343613 | 0.79 | MAPK1 (0.35) | ALOX15MAPK1TP53HSD17B10SMN1; SMN2 | |
| SCHEMBL7981819 | 0.78 | HPGD (0.37) | ALOX15MAPK1TP53HSD17B10SMN1; SMN2 | |
| SCHEMBL1490037 | 0.70 | HPGD (0.47) | RAD51ALOX15MAPK1TP53HSD17B10 | |
| SCHEMBL30545008 | 0.70 | — | — | |
| SCHEMBL20108 | 0.70 | ALOX15 (0.43) | ALOX15MAPK1TP53HSD17B10SMN1; SMN2 | |
| SCHEMBL30442982 | 0.70 | ALOX15 (0.43) | ALOX15MAPK1TP53HSD17B10SMN1; SMN2 | |
| SCHEMBL17627136 | 0.70 | IKBKB (0.41) | MAPK1SMN1; SMN2 | |
| SCHEMBL17686763 | 0.69 | TNIK (0.44) | MAPK1TP53ATMKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118388408-A | Synthesis method of 3, 5-bis (fluoroalkyl) pyrazole compound | 西北师范大学 | 2024-07-26 | — | — | CN | disclosed |
| CN-118388408-A | Synthesis method of 3, 5-bis (fluoroalkyl) pyrazole compound | 西北师范大学 | 2024-07-26 | — | — | CN | disclosed |
| CN-106458918-B | Method for producing 3, 5-bis (haloalkyl) pyrazoles by acylation of ketimines | 拜耳作物科学股份公司 | 2019-07-09 | — | — | CN | disclosed |
| CN-106164049-B | Process for the preparation of 3, 5-di (haloalkyl) pyrazole derivatives from α -dihaloamines and ketimines | 拜耳作物科学股份公司 | 2019-04-12 | — | — | CN | disclosed |
| CN-106458917-B | Pass through the acylated method for preparing bis- (halogenated alkyl) pyrazole derivatives of 3,5- of hydrazone | 拜耳作物科学股份公司 | 2019-04-12 | — | — | CN | disclosed |
| CN-105408314-B | Process for preparing 3, 5-bis (fluoroalkyl) pyrazole derivatives from α -dihaloamines | 拜耳作物科学股份公司 | 2018-04-24 | — | — | CN | disclosed |
| EP-3154946-B1 | PROCESS FOR PREPARING 3,5-BIS(HALOALKYL)PYRAZOLE DERIVATIVES VIA ACYLATION OF HYDRAZONES | BAYER CROPSCIENCE AG (DE) | 2018-04-18 | — | — | EP | disclosed |
| EP-3154947-B1 | PROCESS FOR PREPARING 3,5-BIS(HALOALKYL)PYRAZOLES VIA ACYLATION OF KETIMINES | BAYER CROPSCIENCE AG (DE) | 2018-03-28 | — | — | EP | disclosed |
| US-9914704-B2 | Process for preparing 3,5-bis(haloalkyl)pyrazoles via acylation of ketimines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-13 | — | — | US | disclosed |
| EP-3122727-B1 | PROCESS FOR PREPARING 3,5-BIS(HALOALKYL)PYRAZOLE DERIVATIVES FROM ALPHA , ALPHA-DIHALOAMINES AND KETIMINES | BAYER CROPSCIENCE AG (DE) | 2018-01-31 | — | — | EP | disclosed |
| US-20160108000-A1 | PROCESS FOR PREPARING 3,5-BIS(FLUOROALKYL)PYRAZOLE DERIVATIVES FROM a,a-DIHALOAMINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-04-21 | — | — | US | disclosed |
| CN-105408314-A | Process for preparing 3, 5-bis (fluoroalkyl) pyrazole derivatives from alpha, alpha-dihaloamines | BAYER CROPSCIENCE AG | 2016-03-16 | — | — | CN | disclosed |
| WO-2015189141-A1 | PROCESS FOR PREPARING 3,5-BIS(HALOALKYL)PYRAZOLE DERIVATIVES VIA ACYLATION OF HYDRAZONES | BAYER CROPSCIENCE AG (DE) | 2015-12-17 | — | — | WO | disclosed |
| WO-2015189138-A1 | PROCESS FOR PREPARING 3,5-BIS(HALOALKYL)PYRAZOLES VIA ACYLATION OF KETIMINES | BAYER CROPSCIENCE AG (DE) | 2015-12-17 | — | — | WO | disclosed |
| US-9145370-B2 | Procedure for the decarboxylation of 3,5-bis(haloalkyl)-pyrazole-4-carboxylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2015-09-29 | — | — | US | disclosed |
| US-9145370-B2 | Procedure for the decarboxylation of 3,5-bis(haloalkyl)-pyrazole-4-carboxylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2015-09-29 | — | — | US | disclosed |
| US-20150225350-A1 | PROCEDURE FOR THE DECARBOXYLATION OF 3,5-BIS(HALOALKYL)-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2015-08-13 | — | — | US | disclosed |
| EP-2890682-A1 | PROCEDURE FOR THE DECARBOXYLATION OF 3,5-BIS(HALOALKYL)-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | Bayer CropScience AG (DE) | 2015-07-08 | — | — | EP | disclosed |
| CN-104703972-A | Decarboxylation method of 3, 5-bis (haloalkyl) -pyrazole-4-carboxylic acid derivative | BAYER CROPSCIENCE AG | 2015-06-10 | — | — | CN | disclosed |
| WO-2014033164-A1 | PROCEDURE FOR THE DECARBOXYLATION OF 3,5-BIS(HALOALKYL)-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2014-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160108000-A1 | PROCESS FOR PREPARING 3,5-BIS(FLUOROALKYL)PYRAZOLE DERIVATIVES FROM a,a-DIHALOAMINES | HDHD5, CYP4F3, AADAC | RAD51 3993/4885ALOX15 3214/4885MAPK1 2716/4885 |
| US-20150225350-A1 | PROCEDURE FOR THE DECARBOXYLATION OF 3,5-BIS(HALOALKYL)-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | AOC3, CBR3, AOC2 | RAD51 2207/4885ALOX15 569/4885MAPK1 3908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.