SCHEMBL20108

SCHEMBL20108

FC(F)(F)c1cc(C(F)(F)F)[nH]n1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.43
MAPK1 P28482 2/20 0.43
TP53 P04637 1/20 0.43
HSD17B10 Q99714 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HPGD P15428 1/20 0.40
CA2 P00918 1/20 0.32
CHKA P35790 1/20 0.32
LOX P28300 1/20 0.31
LOXL2 Q9Y4K0 1/20 0.31
CRHBP P24387 1/20 0.31
ATM Q13315 1/20 0.31
CRHR2 Q13324 1/20 0.31
IDO1 P14902 1/20 0.31
LRRK2 Q5S007 1/20 0.30
HSP90AA1 P07900 1/20 0.30
HSP90AB1 P08238 1/20 0.30
MCL1 Q07820 1/20 0.30
MAPT P10636 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30442982 1.00 ALOX15 (0.43) ALOX15MAPK1TP53HSD17B10SMN1; SMN2
SCHEMBL1529233 0.98 ALOX15 (0.42) ALOX15MAPK1TP53HSD17B10SMN1; SMN2
Lithium SCHEMBL31258223 0.98 ALOX15 (0.42) ALOX15MAPK1TP53HSD17B10SMN1; SMN2
SCHEMBL15271218 0.84 MCL1 (0.45) ALOX15MAPK1TP53HSD17B10SMN1; SMN2
SCHEMBL22327730 0.84 HPGD (0.44) ALOX15MAPK1TP53HSD17B10SMN1; SMN2
SCHEMBL13206417 0.84 ALOX15 (0.40) ALOX15MAPK1TP53HSD17B10SMN1; SMN2
SCHEMBL1120183 0.84 HPGD (0.34) ALOX15MAPK1TP53HSD17B10SMN1; SMN2
SCHEMBL15271359 0.81 TP53 (0.37) ALOX15MAPK1TP53HSD17B10SMN1; SMN2
SCHEMBL15271666 0.79 TP53 (0.36) ALOX15MAPK1TP53HSD17B10SMN1; SMN2
SCHEMBL15375205 0.77 CA2 (0.33) CA2CHKAIDO1HSP90AA1HSP90AB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 345 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036614-A Pyrazolyl cyclo trinuclear complex, synthesis method thereof and application thereof in X-ray imaging field 中山大学 2026-05-15 CN claimed
US-20260088352-A1 Heterocyclic Electrolyte Additives for Rechargeable Metal Batteries U S ARMY DEVCOM ARMY RES LABORATORY (US) 2026-03-26 US claimed
US-20240050455-A1 METHODS OF TREATMENT OF A CYTOKINE STORM LOMA LINDA UNIV HEALTH (US) 2024-02-15 US claimed
CN-116678907-A Application of pyrazole ring trinuclear silver (I) complex in determination of organic molecular structure 暨南大学 2023-09-01 CN claimed
CN-116535355-A Novel Cu complex for adsorption separation of propylene propane and preparation method and application thereof 郑州大学 2023-08-04 CN claimed
US-20230223595-A1 Heterocyclic Electrolyte Additives for Rechargeable Metal Batteries THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY 2023-07-13 US claimed
US-11559763-B2 Regenerable solvent mixtures for acid-gas separation RESEARCH TRIANGLE INSTITUTE (US) 2023-01-24 US claimed
CN-115160269-A Arylcarboxamide derivatives as positive allosteric modulators of NMDAR 北京大学 2022-10-11 CN claimed
US-10549233-B2 Regenerable solvent mixtures for acid-gas separation RESEARCH TRIANGLE INSTITUTE (US) 2020-02-04 US claimed
US-10065148-B2 Regenerable solvent mixtures for acid-gas separation RESEARCH TRIANGLE INSTITUTE (US) 2018-09-04 US claimed
WO-2013130997-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION RESEARCH TRIANGLE INSTITUTE (US) 2013-09-06 WO claimed
EP-2611519-A2 REGENERABLE SOLVENT MIXTURES WITH NITROGENOUS BASE FOR ACID-GAS SEPARATION Research Triangle Institute (US) 2013-07-10 EP claimed
US-20130164200-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION RESEARCH TRIANGLE INSTITUTE (US) 2013-06-27 US claimed
WO-2012031281-A2 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION RESEARCH TRIANGLE INSTITUTE (US) 2012-03-08 WO claimed
EP-1542609-A2 METHODS FOR UP-REGULATING ANTIGEN EXPRESSION IN TUMORS Cytocure LLC (US) 2005-06-22 EP claimed
US-20040253235-A1 Methods for up-regualting antigen expression of tumors CYTOCURE LLC 2004-12-16 US claimed
WO-2004019886-A2 METHODS FOR UP-REGULATING ANTIGEN EXPRESSION IN TUMORS CYTOCURE LLC (US) 2004-03-11 WO claimed
US-6106599-A Inks XEROX CORPORATION (US) 2000-08-22 US claimed
US-5897940-A Ink jet transparencies XEROX CORPORATION (US) 1999-04-27 US claimed
US-4321395-A Preparation of acetanilides BASF AKTIENGESELLSCHAFT (DE) 1982-03-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260088352-A1 Heterocyclic Electrolyte Additives for Rechargeable Metal Batteries CA3, CA1, HCN1 ALOX15 3192/4885MAPK1 839/4885TP53 970/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.