SCHEMBL1551979

SCHEMBL1551979

N#CCc1[c]cccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3118969 0.78 MEN1 (0.42)
SCHEMBL483063 0.77
SCHEMBL267285 0.75 ATM (0.44)
SCHEMBL6452089 0.74
SCHEMBL483302 0.74
SCHEMBL614942 0.72
SCHEMBL216358 0.72
SCHEMBL15031 0.72 CALM1 (0.32)
SCHEMBL27458396 0.70
SCHEMBL613453 0.70 PTGS2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230365557-A1 IMIDAZOPYRIDINYL COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE DISORDERS 1ST Biotherapeutics, Inc. (KR) 2023-11-16 US claimed
US-11802126-B2 Imidazopyridinyl compounds and use thereof for treatment of neurodegenerative disorders 1ST Biotherapeutics, Inc. (KR) 2023-10-31 US claimed
EP-3692023-B1 BENZOTHIAZOL COMPOUNDS AND METHODS USING THE SAME FOR TREATING NEURODEGENERATIVE DISORDERS 1ST BIOTHERAPEUTICS INC (KR) 2023-05-17 EP claimed
EP-4011353-A1 NEW COSMETICS SOLVENTS COMPRISING ASCORBIC ACID Beiersdorf AG (DE) 2022-06-15 EP claimed
EP-4011352-A1 NEW COSMETICS SOLVENTS BASED ON THREE DIFFERENT COMPONENTS Beiersdorf AG (DE) 2022-06-15 EP claimed
EP-4011354-A1 NEW COSMETICS SOLVENTS BASED ON TWO DIFFERENT COMPONENTS Beiersdorf AG (DE) 2022-06-15 EP claimed
EP-3927706-A1 IMIDAZOPYRIDINYL COMPOUNDS AND USE THEREOF FOR TREATMENT OF PROLIFERATIVE DISORDERS 1st Biotherapeutics, Inc. (KR) 2021-12-29 EP claimed
EP-3927705-A1 IMIDAZOPYRIDINYL COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE DISORDERS 1st Biotherapeutics, Inc. (KR) 2021-12-29 EP claimed
US-20210347774-A1 IMIDAZOPYRIDINYL COMPOUNDS AND USE THEREOF FOR TREATMENT OF NEURODEGENERATIVE DISORDERS 1ST Biotherapeutics, Inc. 2021-11-11 US claimed
EP-3897644-A1 COMPOUNDS THAT PARTICIPATE IN COOPERATIVE BINDING AND USES THEREOF Revolution Medicines, Inc. (US) 2021-10-27 EP claimed
WO-2006017844-A1 NOVEL 2-AMINO-QUINAZOLINE DERIVATIVES USEFUL AS INHIBITORS OF β-SECRETASE (BACE) JANSSEN PHARMACEUTICA, N.V. (BE) 2006-02-16 WO claimed
US-20050004212-A1 Aryl-substituted acyclic enediyne compounds KAOHSIUNG MEDICAL UNIVERSITY 2005-01-06 US claimed
US-20050004211-A1 Pharmaceutical compositions comprising aryl-substituted acyclic enediyne compounds KAOHSIUNG MEDICAL UNIVERSITY 2005-01-06 US claimed
CN-1492762-A Azoles as malonyl-COA decarboxylase inhibitors useful as metabolic modulators ������ҩ��ʽ���� 2004-04-28 CN claimed
US-6410792-B1 OBESITY DISEASES BAYER CORPORATION 2002-06-25 US claimed
US-6048900-A FOR TREATING EATING DISORDERS, INSULIN RESISTANT DIABETES, HYPERTENSION, HYPERLIPEMIA BAYER CORPORATION (US) 2000-04-11 US claimed
EP-0910565-A1 AMIDE DERIVATIVES AS SELECTIVE NEUROPEPTIDE Y RECEPTOR ANTAGONISTS Bayer Corporation (US) 1999-04-28 EP claimed
WO-1998035957-A1 AMIDE DERIVATIVES AS SELECTIVE NEUROPEPTIDE Y RECEPTOR ANTAGONISTS BAYER CORPORATION (US) 1998-08-20 WO claimed
CN-1042153-A 3-aryloxy methyl-cephalosporins derivatives, their preparation and purposes pharmaceutically SANKYO CO (JP) 1990-05-16 CN claimed
EP-0363223-A2 3-Aryloxymethyl-cephalosporin derivatives, their preparation and their medical use Sankyo Company Limited (JP) 1990-04-11 EP claimed