Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.38 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15518373 | 0.87 | PTGS2 (0.42) | PTGS1PTGS2TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL30999758 | 0.84 | PTGS2 (0.39) | PTGS1PTGS2TP53MAPT | |
| SCHEMBL30999757 | 0.84 | PTGS2 (0.49) | PTGS1PTGS2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7570850 | 0.77 | PTGS1 (0.65) | PTGS1PTGS2L3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL27720508 | 0.76 | PTGS1 (0.46) | PTGS1PTGS2TDP1ALDH1A1CYP1A2 | |
| SCHEMBL1012539 | 0.76 | PTGS1 (0.46) | PTGS1PTGS2L3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL3281219 | 0.76 | MAPK1 (0.56) | PTGS1L3MBTL1ALDH1A1GAACYP1A2 | |
| SCHEMBL27944811 | 0.75 | PTGS1 (0.45) | PTGS1PTGS2TDP1ALDH1A1CYP1A2 | |
| SCHEMBL6456607 | 0.75 | PTGS2 (0.70) | PTGS1PTGS2TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL21849180 | 0.73 | GRN (0.56) | PTGS1PTGS2ALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118388408-A | Synthesis method of 3, 5-bis (fluoroalkyl) pyrazole compound | 西北师范大学 | 2024-07-26 | — | — | CN | disclosed |
| CN-104703972-B | Decarboxylation method of 3, 5-bis (haloalkyl) -pyrazole-4-carboxylic acid derivative | 拜耳农作物科学股份公司 | 2017-05-31 | — | — | CN | disclosed |
| EP-2890682-B1 | PROCEDURE FOR THE DECARBOXYLATION OF 3,5-BIS(HALOALKYL)-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2016-06-29 | — | — | EP | disclosed |
| EP-2890682-B1 | PROCEDURE FOR THE DECARBOXYLATION OF 3,5-BIS(HALOALKYL)-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2016-06-29 | — | — | EP | disclosed |
| US-9145370-B2 | Procedure for the decarboxylation of 3,5-bis(haloalkyl)-pyrazole-4-carboxylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2015-09-29 | — | — | US | disclosed |
| US-9145370-B2 | Procedure for the decarboxylation of 3,5-bis(haloalkyl)-pyrazole-4-carboxylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2015-09-29 | — | — | US | disclosed |
| US-20150225350-A1 | PROCEDURE FOR THE DECARBOXYLATION OF 3,5-BIS(HALOALKYL)-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2015-08-13 | — | — | US | disclosed |
| US-20150225350-A1 | PROCEDURE FOR THE DECARBOXYLATION OF 3,5-BIS(HALOALKYL)-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2015-08-13 | — | — | US | disclosed |
| EP-2890682-A1 | PROCEDURE FOR THE DECARBOXYLATION OF 3,5-BIS(HALOALKYL)-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | Bayer CropScience AG (DE) | 2015-07-08 | — | — | EP | disclosed |
| CN-104703972-A | Decarboxylation method of 3, 5-bis (haloalkyl) -pyrazole-4-carboxylic acid derivative | BAYER CROPSCIENCE AG | 2015-06-10 | — | — | CN | disclosed |
| WO-2014033164-A1 | PROCEDURE FOR THE DECARBOXYLATION OF 3,5-BIS(HALOALKYL)-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2014-03-06 | — | — | WO | disclosed |
| WO-2014033164-A1 | PROCEDURE FOR THE DECARBOXYLATION OF 3,5-BIS(HALOALKYL)-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2014-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150225350-A1 | PROCEDURE FOR THE DECARBOXYLATION OF 3,5-BIS(HALOALKYL)-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | AOC3, CBR3, AOC2 | PTGS1 2494/4885PTGS2 2497/4885TDP1 4715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.