Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 18/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15519728 | 0.89 | TRPM8 (0.42) | TRPM8L3MBTL1 | |
| SCHEMBL15519817 | 0.89 | TRPM8 (0.37) | TRPM8 | |
| SCHEMBL14053670 | 0.88 | TRPM8 (0.40) | TRPM8PPARD | |
| SCHEMBL15519980 | 0.87 | PPARG (0.40) | TRPM8PPARD | |
| SCHEMBL14053977 | 0.81 | CYP3A4 (0.36) | PPARD | |
| SCHEMBL15519675 | 0.81 | TRPM8 (0.34) | TRPM8PPARD | |
| SCHEMBL15519981 | 0.80 | TRPM8 (0.36) | TRPM8PPARD | |
| SCHEMBL14054203 | 0.79 | RORC (0.38) | PPARD | |
| SCHEMBL15519975 | 0.79 | TP53 (0.39) | TRPM8L3MBTL1 | |
| SCHEMBL15520543 | 0.78 | RXRA (0.39) | TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2521727-B1 | NEW BENZOIC PYRROLOPYRIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF PARKINSON'S DISEASE | INVENTIVA (FR) | 2014-03-19 | — | — | EP | claimed |