Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1551475 | 0.82 | PTGIR (0.46) | ALDH1A1RAB9AKMT2AMAPTHPGD | |
| SCHEMBL1552501 | 0.78 | KMT2A (0.40) | ALDH1A1RAB9AKMT2ABCHE | |
| SCHEMBL1552089 | 0.75 | NFKB1 (0.41) | ALDH1A1TDP1LMNA | |
| SCHEMBL1552094 | 0.74 | MGLL (0.46) | ALDH1A1RAB9AKMT2AL3MBTL1LMNA | |
| SCHEMBL1552752 | 0.72 | HPGD (0.39) | ALDH1A1MAPTHPGD | |
| SCHEMBL12598575 | 0.72 | KMT2A (0.54) | EPHX1ALDH1A1RAB9AKMT2ATDP1 | |
| SCHEMBL15705238 | 0.72 | KMT2A (0.54) | EPHX1ALDH1A1RAB9AKMT2ATDP1 | |
| SCHEMBL16248428 | 0.72 | KMT2A (0.54) | EPHX1ALDH1A1RAB9AKMT2ATDP1 | |
| SCHEMBL13555711 | 0.72 | KMT2A (0.54) | EPHX1ALDH1A1RAB9AKMT2ATDP1 | |
| SCHEMBL10230770 | 0.72 | KMT2A (0.54) | EPHX1ALDH1A1RAB9AKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891035-B1 | SUBSTITUTED BENZO-CONDENSED CYCLOHEPTANONE DERIVATIVES AND THEIR USE FOR PRODUCING DRUGS | GRUENENTHAL GMBH (DE) | 2011-04-27 | — | — | EP | claimed |
| US-7858613-B2 | Substituted benzo-condensed cycloheptanone derivatives and their use for producing drugs | GRUENENTHAL GMBH (DE) | 2010-12-28 | — | — | US | claimed |
| US-20090215858-A1 | Substituted Benzo-Condensed Cycloheptanone Derivatives And Their Use For Producing Drugs | GRUENENTHAL GMBH (DE) | 2009-08-27 | — | — | US | claimed |
| US-7858613-B2 | Substituted benzo-condensed cycloheptanone derivatives and their use for producing drugs | GRUENENTHAL GMBH (DE) | 2010-12-28 | — | — | US | disclosed |
| US-20090215858-A1 | Substituted Benzo-Condensed Cycloheptanone Derivatives And Their Use For Producing Drugs | GRUENENTHAL GMBH (DE) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215858-A1 | Substituted Benzo-Condensed Cycloheptanone Derivatives And Their Use For Producing Drugs | ABCB1, DHFR, DHPS | EPHX1 1122/4885ALDH1A1 613/4885RAB9A 4019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.