Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27849711 | 0.81 | TSHR (0.48) | ALDH1A1PDK2TSHRFEN1PDK1 | |
| SCHEMBL20973133 | 0.76 | CES2 (0.46) | ALDH1A1HPGDCYP1A2TSHRFEN1 | |
| SCHEMBL28013748 | 0.74 | — | — | |
| SCHEMBL17981534 | 0.73 | POLB (0.44) | ALDH1A1PDK2CYP1A2TSHRGAA | |
| SCHEMBL2689384 | 0.71 | GRM4 (0.36) | ALDH1A1TLR7TSHRGAALMNA | |
| SCHEMBL673460 | 0.70 | ALDH1A1 (0.56) | ALDH1A1HPGDTYK2CYP1A2CYP2A6 | |
| Trifluoroacetic Acid SCHEMBL3979025 | 0.70 | ALDH1A1 (0.50) | ALDH1A1HPGDTYK2TLR7TSHR | |
| SCHEMBL13689692 | 0.69 | ALDH1A1 (0.48) | ALDH1A1HPGDTYK2CYP1A2CYP2A6 | |
| SCHEMBL112191 | 0.68 | PARP1 (0.47) | ALDH1A1HPGDTSHRFEN1GAA | |
| SCHEMBL25412744 | 0.67 | TSHR (0.39) | ALDH1A1HPGDTSHRGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180098542-A1 | METHODS OF PEST CONTROL IN SOYBEAN | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-12 | — | — | US | disclosed |
| US-9867375-B2 | Methods of pest control in soybean | SYNGENTA PARTICIPATIONS AG (CH) | 2018-01-16 | — | — | US | disclosed |
| US-20150237862-A1 | METHODS OF PEST CONTROL IN SOYBEAN | SYNGENTA PARTICIPATIONS AG (CH) | 2015-08-27 | — | — | US | disclosed |
| US-20150208658-A1 | METHODS OF SOIL PEST CONTROL | SYNGENTA PARTICIPATIONS AG (CH) | 2015-07-30 | — | — | US | disclosed |
| US-20150189884-A1 | METHODS OF CONTROLLING INSECTS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-07-09 | — | — | US | disclosed |
| EP-2887802-A2 | METHODS OF SOIL PEST CONTROL | Syngenta Participations AG (CH) | 2015-07-01 | — | — | EP | disclosed |
| WO-2014029706-A2 | METHODS OF CONTROLLING INSECTS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-27 | — | — | WO | disclosed |
| WO-2014029707-A1 | METHODS OF CONTROLLING INSECTS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-27 | — | — | WO | disclosed |
| WO-2014029708-A1 | METHODS OF CONTROLLING INSECTS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-27 | — | — | WO | disclosed |
| WO-2014029710-A2 | METHODS OF SOIL PEST CONTROL | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180098542-A1 | METHODS OF PEST CONTROL IN SOYBEAN | BTF3, BRS3, CCNB3 | ALDH1A1 4511/4885PDK2 3685/4885HPGD 4055/4885 |
| US-20150189884-A1 | METHODS OF CONTROLLING INSECTS | CBR3, C5, CNPY3 | ALDH1A1 4341/4885PDK2 4613/4885HPGD 4158/4885 |
| US-20150208658-A1 | METHODS OF SOIL PEST CONTROL | C1S, CBR3, CNPY3 | ALDH1A1 3946/4885PDK2 4338/4885HPGD 4142/4885 |
| US-20150237862-A1 | METHODS OF PEST CONTROL IN SOYBEAN | HRH4, HRH3, H1-3 | ALDH1A1 4444/4885PDK2 3358/4885HPGD 3899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.