Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 3/20 | 0.48 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.48 |
| ▸ | ALB | P02768 | 2/20 | 0.47 |
| ▸ | SELL | P14151 | 2/20 | 0.46 |
| ▸ | SELP | P16109 | 2/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA7 | P43166 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.45 |
| ▸ | CES2 | O00748 | 2/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2791251 | 0.86 | AKR1C2 (0.58) | AKR1C2AKR1C1ALBSELLSELP | |
| SCHEMBL29695966 | 0.86 | AKR1C2 (0.58) | AKR1C2AKR1C1ALBSELLSELP | |
| SCHEMBL22133771 | 0.80 | MEN1 (0.46) | ALDH1A1CA9CA14CES2CES1 | |
| SCHEMBL30845519 | 0.80 | MEN1 (0.46) | ALDH1A1CA9CA14CES2CES1 | |
| SCHEMBL23302962 | 0.78 | HMGB1 (0.58) | AKR1C2AKR1C1ALBKEAP1ALDH1A1 | |
| SCHEMBL31284332 | 0.78 | AKR1C2 (0.64) | AKR1C2AKR1C1ALBKEAP1CES2 | |
| SCHEMBL20944591 | 0.78 | AKR1C2 (0.64) | AKR1C2AKR1C1ALBKEAP1CES2 | |
| SCHEMBL1006776 | 0.78 | KEAP1 (0.57) | AKR1C2AKR1C1ALBKEAP1ALDH1A1 | |
| SCHEMBL6175690 | 0.78 | KEAP1 (0.42) | AKR1C2AKR1C1ALBKEAP1ALDH1A1 | |
| SCHEMBL6241684 | 0.78 | AKR1C2 (0.64) | AKR1C2AKR1C1KEAP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250122182-A1 | MYST Inhibitors | Isosterix, Inc. | 2025-04-17 | — | — | US | disclosed |
| CN-116969971-A | Nitrogen-containing macrocyclic compound, and preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2023-10-31 | — | — | CN | disclosed |
| US-9079989-B2 | Charge control resin and manufacturing method of the same | ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) | 2015-07-14 | — | — | US | disclosed |
| US-20150025213-A1 | CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME | ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) | 2015-01-22 | — | — | US | disclosed |
| US-8883946-B2 | Charge control resin and manufacturing method of the same | ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) | 2014-11-11 | — | — | US | disclosed |
| US-20140080989-A1 | CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME | ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) | 2014-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250122182-A1 | MYST Inhibitors | MNAT1, SUGT1, ACAT2 | AKR1C2 3165/4885AKR1C1 3221/4885ALB 4654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.