Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | CA12 | O43570 | 3/20 | 0.59 |
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | CA7 | P43166 | 3/20 | 0.59 |
| ▸ | CA9 | Q16790 | 3/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.52 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15941312 | 0.92 | HNF4A (0.74) | HNF4AALDH1A1CA12CA1CA2 | |
| SCHEMBL15524796 | 0.92 | ALDH1A1 (0.55) | HNF4AALDH1A1CA12CA1CA2 | |
| SCHEMBL15631831 | 0.86 | CA12 (0.57) | HNF4AALDH1A1CA12CA1CA2 | |
| SCHEMBL7605479 | 0.84 | ALDH1A1 (0.47) | HNF4AALDH1A1CA12CA1CA2 | |
| SCHEMBL7615611 | 0.83 | ALDH1A1 (0.55) | HNF4AALDH1A1CA12CA1CA2 | |
| SCHEMBL4962858 | 0.83 | XDH (0.68) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL20503723 | 0.82 | HNF4A (0.60) | HNF4AALDH1A1CA12CA1CA2 | |
| SCHEMBL21679889 | 0.82 | HNF4A (0.60) | HNF4AALDH1A1CA12CA1CA2 | |
| SCHEMBL27178395 | 0.80 | HNF4A (0.63) | HNF4AALDH1A1CA12CA1CA2 | |
| SCHEMBL19342932 | 0.80 | RARB (0.68) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11426714-B2 | Metal organic frameworks (MOFs) and methods of synthesizing and using the same | VIETNAM NATIONAL UNIVERSITY HO CHI MINH CITY (VN) | 2022-08-30 | — | — | US | claimed |
| US-20210162388-A1 | METAL ORGANIC FRAMEWORKS (MOFs) AND METHODS OF SYNTHESIZING AND USING THE SAME | Center for Innovative Materials and Architectures (VN) | 2021-06-03 | — | — | US | claimed |
| US-11426714-B2 | Metal organic frameworks (MOFs) and methods of synthesizing and using the same | VIETNAM NATIONAL UNIVERSITY HO CHI MINH CITY (VN) | 2022-08-30 | — | — | US | disclosed |
| US-20210162388-A1 | METAL ORGANIC FRAMEWORKS (MOFs) AND METHODS OF SYNTHESIZING AND USING THE SAME | Center for Innovative Materials and Architectures (VN) | 2021-06-03 | — | — | US | disclosed |
| US-20210162388-A1 | METAL ORGANIC FRAMEWORKS (MOFs) AND METHODS OF SYNTHESIZING AND USING THE SAME | Center for Innovative Materials and Architectures (VN) | 2021-06-03 | — | — | US | disclosed |
| US-9139600-B2 | Acetylene bridged linkers and metal-organic frameworks (MOFs) produced thereof | BASF SE (DE) | 2015-09-22 | — | — | US | disclosed |
| US-9139600-B2 | Acetylene bridged linkers and metal-organic frameworks (MOFs) produced thereof | BASF SE (DE) | 2015-09-22 | — | — | US | disclosed |
| US-9139600-B2 | Acetylene bridged linkers and metal-organic frameworks (MOFs) produced thereof | BASF SE (DE) | 2015-09-22 | — | — | US | disclosed |
| EP-2897929-A1 | ACETYLENE BRIDGED LINKERS AND METAL-ORGANIC FRAMEWORKS (MOFS) PRODUCED THEREOF | BASF SE (DE) | 2015-07-29 | — | — | EP | disclosed |
| CN-104797548-A | Acetylene bridging linkers and Metal Organic Frameworks (MOFs) prepared therefrom | BASF SE | 2015-07-22 | — | — | CN | disclosed |
| WO-2014045135-A1 | ACETYLENE BRIDGED LINKERS AND METAL-ORGANIC FRAMEWORKS (MOFS) PRODUCED THEREOF | BASF SE (DE) | 2014-03-27 | — | — | WO | disclosed |
| WO-2014045135-A1 | ACETYLENE BRIDGED LINKERS AND METAL-ORGANIC FRAMEWORKS (MOFS) PRODUCED THEREOF | BASF SE (DE) | 2014-03-27 | — | — | WO | disclosed |
| US-20140081044-A1 | Acetylene Bridged Linkers and Metal-Organic Frameworks (MOFs) Produced Thereof | BASF SE (DE) | 2014-03-20 | — | — | US | disclosed |
| US-20140081044-A1 | Acetylene Bridged Linkers and Metal-Organic Frameworks (MOFs) Produced Thereof | BASF SE (DE) | 2014-03-20 | — | — | US | disclosed |
| US-20140081044-A1 | Acetylene Bridged Linkers and Metal-Organic Frameworks (MOFs) Produced Thereof | BASF SE (DE) | 2014-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140081044-A1 | Acetylene Bridged Linkers and Metal-Organic Frameworks (MOFs) Produced Thereof | B3GNT2, KAT8, MDH2 | HNF4A 2426/4885ALDH1A1 1647/4885CA12 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.