SCHEMBL15524402

SCHEMBL15524402

COc1c(F)cc(C(=O)O)c(O)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
HSD17B10 Q99714 1/20 0.43
AKR1C2 P52895 1/20 0.42
AKR1C1 Q04828 1/20 0.42
PTGS2 P35354 1/20 0.42
PKM P14618 2/20 0.40
ALB P02768 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA3 P07451 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
CA5A P35218 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
CA5B Q9Y2D0 1/20 0.40
TPMT P51580 4/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27879635 0.87 MAPT (0.46) MAPTTDP1HSD17B10AKR1C2AKR1C1
SCHEMBL27540803 0.81 HSD17B10 (0.50) MAPTTDP1HSD17B10PKMTPMT
SCHEMBL28424948 0.79 HSD17B10 (0.44) MAPTTDP1HSD17B10PKMTPMT
SCHEMBL6422815 0.79 HSD17B10 (0.44) MAPTTDP1HSD17B10PKMTPMT
SCHEMBL7352417 0.79 MAPT (0.45) MAPTTDP1HSD17B10AKR1C2AKR1C1
SCHEMBL30666042 0.78 HSD17B10 (0.43) MAPTTDP1HSD17B10PKMTPMT
SCHEMBL21262467 0.78 TDP1 (0.66) MAPTTDP1HSD17B10AKR1C2AKR1C1
SCHEMBL18677528 0.77 TDP1 (0.55) MAPTTDP1HSD17B10PTGS2PKM
SCHEMBL419090 0.77 TDP1 (0.50) MAPTTDP1HSD17B10PTGS2PKM
SCHEMBL28583415 0.76 MEN1 (0.42) MAPTTDP1HSD17B10PKMCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9079989-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-07-14 US disclosed
US-20150025213-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2015-01-22 US disclosed
US-8883946-B2 Charge control resin and manufacturing method of the same ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-11-11 US disclosed
US-20140080989-A1 CHARGE CONTROL RESIN AND MANUFACTURING METHOD OF THE SAME ORIENT CHEMICAL INDUSTRIES CO., LTD. (JP) 2014-03-20 US disclosed