Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | TPMT | P51580 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15524402 | 0.87 | MAPT (0.47) | MAPTTDP1HSD17B10HSD17B1HSD17B2 | |
| SCHEMBL28113807 | 0.86 | HSD17B1 (0.43) | MAPTTDP1HSD17B1HSD17B2TPMT | |
| SCHEMBL6422815 | 0.85 | HSD17B10 (0.44) | MAPTTDP1HSD17B10PKMTPMT | |
| SCHEMBL28424948 | 0.85 | HSD17B10 (0.44) | MAPTTDP1HSD17B10PKMTPMT | |
| SCHEMBL28937180 | 0.85 | HSD17B1 (0.47) | MAPTTDP1HSD17B10HSD17B1HSD17B2 | |
| SCHEMBL28147538 | 0.84 | KDM4E (0.43) | MAPTTDP1HSD17B10HSD17B1HSD17B2 | |
| SCHEMBL607945 | 0.81 | HSD17B10 (0.44) | MAPTTDP1HSD17B10HSD17B1HSD17B2 | |
| SCHEMBL27927680 | 0.80 | HSD17B10 (0.43) | MAPTTDP1HSD17B10HSD17B1HSD17B2 | |
| SCHEMBL27540803 | 0.79 | HSD17B10 (0.50) | MAPTTDP1HSD17B10PKMTPMT | |
| SCHEMBL27836209 | 0.79 | TSHR (0.46) | MAPTHSD17B1HSD17B2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102731378-A | Preparation method of 3-hydroxyl-N-(3,5-dichloropyridine-4-group)-4-(difluoromethoxy)benzamide | SICHUAN SHUZHONG PHARMACEUTICAL CO LTD | 2012-10-17 | — | — | CN | claimed |
| CN-102731378-A | Preparation method of 3-hydroxyl-N-(3,5-dichloropyridine-4-group)-4-(difluoromethoxy)benzamide | SICHUAN SHUZHONG PHARMACEUTICAL CO LTD | 2012-10-17 | — | — | CN | disclosed |
| CN-102731378-A | Preparation method of 3-hydroxyl-N-(3,5-dichloropyridine-4-group)-4-(difluoromethoxy)benzamide | SICHUAN SHUZHONG PHARMACEUTICAL CO LTD | 2012-10-17 | — | — | CN | disclosed |