SCHEMBL1552455

SCHEMBL1552455

C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)CN)C(N)=O

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 12/20 0.44
OPRK1 P41145 12/20 0.44
APLNR P35414 1/20 0.42
EPHA2 P29317 2/20 0.40
CAPN1 P07384 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1552452 1.00 OPRM1 (0.44) OPRM1OPRK1APLNREPHA2CAPN1
SCHEMBL1552457 0.94 OPRM1 (0.43) OPRM1OPRK1APLNREPHA2
SCHEMBL1552453 0.94 OPRM1 (0.43) OPRM1OPRK1APLNREPHA2
SCHEMBL5863304 0.91 EPHA2 (0.41) OPRM1OPRK1APLNREPHA2
SCHEMBL4190053 0.90 ACE (0.42) OPRM1OPRK1APLNREPHA2
SCHEMBL4190057 0.90 ACE (0.42) OPRM1OPRK1APLNREPHA2
SCHEMBL10340262 0.90 ACE (0.42) OPRM1OPRK1APLNREPHA2
SCHEMBL31124688 0.90 OPRM1 (0.41) OPRM1OPRK1EPHA2
SCHEMBL7444428 0.90 ACE (0.42) OPRM1OPRK1APLNREPHA2
SCHEMBL27445701 0.90 ACE (0.42) OPRM1OPRK1APLNREPHA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1833571-B1 COSMETIC COMPOSITION FOR SKIN APPLICATION SUITABLE FOR RELAXING EXPRESSION WRINKLES LABO COSPROPHAR AG (CH) 2011-04-27 EP claimed
US-7846483-B2 Cosmetic composition for skin application suitable for relaxing expression wrinkles LABO COSPROPHAR AG (CH) 2010-12-07 US claimed
EP-1833571-A1 COSMETIC COMPOSITION FOR SKIN APPLICATION SUITABLE FOR RELAXING EXPRESSION WRINKLES LABO Cosprophar AG (CH) 2007-09-19 EP claimed
US-20070148118-A1 Cosmetic composition for skin application suitable for relaxing expression wrinkles LABO COSPROPHAR AG (CH) 2007-06-28 US claimed
WO-2006069608-A1 COSMETIC COMPOSITION FOR SKIN APPLICATION SUITABLE FOR RELAXING EXPRESSION WRINKLES LABO COSPROPHAR AG (CH) 2006-07-06 WO claimed
US-20250049688-A1 COMPOSITION FOR COSMETIC USE PROFESSIONAL DERMA SA (CH) 2025-02-13 US disclosed
EP-4401703-A2 INJECTABLE COMPOSITION COMPRISING HYALURONIC ACID AND AMINO ACIDS Professional Derma SA (CH) 2024-07-24 EP disclosed
WO-2023042119-A2 COMPOSITION FOR COSMETIC USE PROFESSIONAL DERMA SA (CH) 2023-03-23 WO disclosed
CN-113301910-B Skin rejuvenation and healing mixtures of peptide components and uses thereof 环球科技创新有限股份公司 2023-02-03 CN disclosed
EP-1833571-B1 COSMETIC COMPOSITION FOR SKIN APPLICATION SUITABLE FOR RELAXING EXPRESSION WRINKLES LABO COSPROPHAR AG (CH) 2011-04-27 EP disclosed
US-7846483-B2 Cosmetic composition for skin application suitable for relaxing expression wrinkles LABO COSPROPHAR AG (CH) 2010-12-07 US disclosed
US-7741124-B2 Detection procedures for fibrinogen and/or fibrinogen derivatives STIEF THOMAS W 2010-06-22 US disclosed
US-20090176310-A1 DETECTION PROCEDURES FOR FIBRINOGEN AND/OR FIBRINOGEN DERIVATIVES STIEF THOMAS W 2009-07-09 US disclosed
US-7510879-B2 Using matrix independent turbidimetry to determine fibrinogen concentration and diagnose/prognose atherothrombotic diseases STIEF THOMAS W 2009-03-31 US disclosed
EP-1833571-A1 COSMETIC COMPOSITION FOR SKIN APPLICATION SUITABLE FOR RELAXING EXPRESSION WRINKLES LABO Cosprophar AG (CH) 2007-09-19 EP disclosed
US-20070148118-A1 Cosmetic composition for skin application suitable for relaxing expression wrinkles LABO COSPROPHAR AG (CH) 2007-06-28 US disclosed
WO-2006069608-A1 COSMETIC COMPOSITION FOR SKIN APPLICATION SUITABLE FOR RELAXING EXPRESSION WRINKLES LABO COSPROPHAR AG (CH) 2006-07-06 WO disclosed
US-20040253739-A1 Detection procedures for fibrinogen and/or fibrinogen derivatives STIEF THOMAS W (DE) 2004-12-16 US disclosed