SCHEMBL1552457

SCHEMBL1552457

C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)CN)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 11/20 0.43
OPRK1 P41145 11/20 0.43
APLNR P35414 1/20 0.41
EPHA2 P29317 2/20 0.41
NMUR2 Q9GZQ4 2/20 0.40
NMUR1 Q9HB89 2/20 0.40
GRB2 P62993 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1552453 1.00 OPRM1 (0.43) OPRM1OPRK1APLNREPHA2NMUR2
SCHEMBL1552452 0.94 OPRM1 (0.44) OPRM1OPRK1APLNREPHA2
SCHEMBL1552455 0.94 OPRM1 (0.44) OPRM1OPRK1APLNREPHA2
SCHEMBL31124688 0.93 OPRM1 (0.41) OPRM1OPRK1EPHA2NMUR2NMUR1
SCHEMBL29802182 0.92 OPRM1 (0.44) OPRM1OPRK1EPHA2NMUR2NMUR1
SCHEMBL10340262 0.91 ACE (0.42) OPRM1OPRK1APLNREPHA2
SCHEMBL4190053 0.91 ACE (0.42) OPRM1OPRK1APLNREPHA2
SCHEMBL4190057 0.91 ACE (0.42) OPRM1OPRK1APLNREPHA2
SCHEMBL7444428 0.91 ACE (0.42) OPRM1OPRK1APLNREPHA2
SCHEMBL27445701 0.91 ACE (0.42) OPRM1OPRK1APLNREPHA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747264-A1 MICELLAR BIOACTIVE COLLAGEN-STIMULATING LIPOPEPTIDE University of Reading (GB) 2026-05-27 EP claimed
WO-2025037123-A1 MICELLAR BIOACTIVE COLLAGEN-STIMULATING LIPOPEPTIDE UNIVERSITY OF READING (GB) 2025-02-20 WO claimed
EP-4747264-A1 MICELLAR BIOACTIVE COLLAGEN-STIMULATING LIPOPEPTIDE University of Reading (GB) 2026-05-27 EP disclosed
WO-2025037123-A1 MICELLAR BIOACTIVE COLLAGEN-STIMULATING LIPOPEPTIDE UNIVERSITY OF READING (GB) 2025-02-20 WO disclosed
US-20240304334-A1 CLOTTABILITY-BASED PERSONALIZED TREATMENT (CPT) SYSTEM PUN SAN (CH) 2024-09-12 US disclosed
CN-115894625-B Polypeptide with anti-aging effect and application thereof 桂林医学院 2024-08-27 CN disclosed
US-20240076314-A1 PEPTIDE COMPOSITIONS AND METHODS FOR INHIBITING NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVITY GLO PHARMA, INC. 2024-03-07 US disclosed
CN-117561450-A Personalized Therapy (CPT) system based on clotting capabilities 潘山 2024-02-13 CN disclosed
CN-115894625-A Polypeptide with anti-aging effect and application thereof 桂林医学院 2023-04-04 CN disclosed
CN-115702161-A Peptide compositions and methods for inhibiting nicotinic acetylcholine receptor activity 格罗制药公司 2023-02-14 CN disclosed
EP-1833571-B1 COSMETIC COMPOSITION FOR SKIN APPLICATION SUITABLE FOR RELAXING EXPRESSION WRINKLES LABO COSPROPHAR AG (CH) 2011-04-27 EP disclosed
US-7846483-B2 Cosmetic composition for skin application suitable for relaxing expression wrinkles LABO COSPROPHAR AG (CH) 2010-12-07 US disclosed
EP-1833571-A1 COSMETIC COMPOSITION FOR SKIN APPLICATION SUITABLE FOR RELAXING EXPRESSION WRINKLES LABO Cosprophar AG (CH) 2007-09-19 EP disclosed
US-20070148118-A1 Cosmetic composition for skin application suitable for relaxing expression wrinkles LABO COSPROPHAR AG (CH) 2007-06-28 US disclosed
WO-2006069608-A1 COSMETIC COMPOSITION FOR SKIN APPLICATION SUITABLE FOR RELAXING EXPRESSION WRINKLES LABO COSPROPHAR AG (CH) 2006-07-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240076314-A1 PEPTIDE COMPOSITIONS AND METHODS FOR INHIBITING NICOTINIC ACETYLCHOLINE RECEPTOR ACTIVITY CHRNB1, CHRNG, CHRNA1 OPRM1 2825/4885OPRK1 2549/4885APLNR 46/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.