SCHEMBL477489

SCHEMBL477489

OCc1ccccc1-c1ccsc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.47
CYP2B6 P20813 2/20 0.47
CYP2E1 P05181 1/20 0.47
PDCD1 Q15116 1/20 0.43
CD274 Q9NZQ7 1/20 0.43
PTPRC P08575 1/20 0.41
DPP4 P27487 1/20 0.39
GPR84 Q9NQS5 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
KIT P10721 1/20 0.39
FLT1 P17948 1/20 0.39
KDR P35968 1/20 0.39
PDK2 Q15119 2/20 0.39
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
MAOB P27338 1/20 0.38
ADRA1D P25100 1/20 0.38
ADRA1A P35348 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6598549 0.84 MEN1 (0.39) CYP2A6CYP2B6CYP2E1PTPRCCYP3A4
SCHEMBL13824218 0.82 CD274 (0.64) CYP2A6CYP2B6CYP2E1PDCD1CD274
SCHEMBL3181212 0.81 CYP2A6 (0.47) CYP2A6CYP2B6CYP2E1PDCD1CD274
SCHEMBL21480391 0.81 CYP2A6 (0.47) CYP2A6CYP2B6CYP2E1PTPRCDPP4
SCHEMBL10902241 0.81 CYP2A6 (0.47) CYP2A6CYP2B6CYP2E1PTPRCDPP4
SCHEMBL8279414 0.81 DPP4 (0.59) CYP2A6CYP2B6CYP2E1PTPRCDPP4
SCHEMBL12819940 0.81 CYP2A6 (0.47) CYP2A6CYP2B6CYP2E1PTPRCCYP3A4
SCHEMBL7502553 0.81 CYP2A6 (0.47) CYP2A6CYP2B6CYP2E1PTPRCDPP4
SCHEMBL30340124 0.81 CYP2A6 (0.47) CYP2A6CYP2B6CYP2E1PTPRCCYP3A4
SCHEMBL4946960 0.79 CYP2A6 (0.64) CYP2A6CYP2B6CYP2E1PTPRCGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8563786-B2 Method for producing optically active alcohol MITSUI CHEMICALS, INC. (JP) 2013-10-22 US disclosed
US-20120088938-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2012-04-12 US disclosed
EP-2412694-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL Mitsui Chemicals, Inc. (JP) 2012-02-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120088938-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL ADH1A, ADH1C, FHIT CYP2A6 66/4885CYP2B6 111/4885CYP2E1 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.