Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | FBP1 | P09467 | 3/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL567063 | 1.00 | ALDH1A1 (0.56) | ALDH1A1TSHRFBP1AKR1C3CYP2A6 | |
| SCHEMBL567062 | 1.00 | ALDH1A1 (0.56) | ALDH1A1TSHRFBP1AKR1C3CYP2A6 | |
| Methyl Alcohol SCHEMBL28258074 | 0.96 | ALDH1A1 (0.57) | ALDH1A1TSHRFBP1AKR1C3CYP2A6 | |
| Methyl Alcohol SCHEMBL28258076 | 0.96 | ALDH1A1 (0.57) | ALDH1A1TSHRFBP1AKR1C3CYP2A6 | |
| SCHEMBL11776320 | 0.88 | ALDH1A1 (0.46) | ALDH1A1TSHRFBP1AKR1C3CYP2A6 | |
| SCHEMBL38655330 | 0.79 | LMNA (0.42) | ALDH1A1TSHRAKR1C3CYP2A6MAPT | |
| SCHEMBL28470411 | 0.77 | CYP2A6 (0.50) | ALDH1A1TSHRAKR1C3CYP2A6MAPT | |
| SCHEMBL28472160 | 0.77 | HSD17B10 (0.50) | ALDH1A1FBP1AKR1C3HTTAKR1C1 | |
| SCHEMBL28470407 | 0.77 | CYP2A6 (0.50) | ALDH1A1TSHRAKR1C3CYP2A6MAPT | |
| SCHEMBL38655327 | 0.77 | FBP1 (0.53) | ALDH1A1FBP1MAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122010897-A | Naphthiophene compound, preparation method and application | 新疆大学 | 2026-05-12 | — | — | CN | disclosed |
| CN-113150588-A | Water-based environment-friendly wood paint and preparation method thereof | 尤纪超 | 2021-07-23 | — | — | CN | disclosed |
| CN-113025099-A | Graphene coating and preparation method thereof | 尤纪超 | 2021-06-25 | — | — | CN | disclosed |
| CN-111466378-A | Synergist and insecticide and bactericide containing same | 山东德浩化学有限公司 | 2020-07-31 | — | — | CN | disclosed |
| EP-1844026-B1 | MORPHOLINES AS 5HT2C AGONISTS | HOFFMANN LA ROCHE (CH) | 2011-04-27 | — | — | EP | disclosed |
| US-7323466-B2 | Morpholine derivatives as 5HT2C receptor agonists for the treatment of obesity | HOFFMAN-LA ROCHE INC. (US) | 2008-01-29 | — | — | US | disclosed |
| US-7323466-B2 | Morpholine derivatives as 5HT2C receptor agonists for the treatment of obesity | HOFFMAN-LA ROCHE INC. (US) | 2008-01-29 | — | — | US | disclosed |
| US-7323466-B2 | Morpholine derivatives as 5HT2C receptor agonists for the treatment of obesity | HOFFMAN-LA ROCHE INC. (US) | 2008-01-29 | — | — | US | disclosed |
| US-20060178510-A1 | New morpholine derivatives as 5HT2C receptor agonists for the treatment of obesity | HOFFMANN-LA ROCHE INC. | 2006-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178510-A1 | New morpholine derivatives as 5HT2C receptor agonists for the treatment of obesity | HTR2C, HTR1A, HTR1B | ALDH1A1 541/4885TSHR 201/4885FBP1 2697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.