Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746687 | 0.82 | ALDH1A1 (0.64) | MAPTALDH1A1POLBIDO1MAPK1 | |
| SCHEMBL9570633 | 0.77 | MAPT (0.58) | MAPTALDH1A1POLBIDO1MAPK1 | |
| SCHEMBL7297643 | 0.77 | MAPT (0.58) | MAPTALDH1A1POLBIDO1MAPK1 | |
| SCHEMBL11453242 | 0.77 | MAPT (0.51) | MAPTALDH1A1POLBIDO1MAPK1 | |
| SCHEMBL88305 | 0.76 | TSHR (0.55) | ALDH1A1POLBIDO1LOXL2 | |
| SCHEMBL8811170 | 0.75 | MAPT (0.58) | MAPTALDH1A1POLBIDO1MAPK1 | |
| SCHEMBL9395356 | 0.75 | MAPT (0.57) | MAPTALDH1A1POLBIDO1MAPK1 | |
| SCHEMBL6513576 | 0.75 | ALDH1A1 (0.49) | MAPTALDH1A1MAPK1TDP1KDM4E | |
| SCHEMBL5280249 | 0.75 | MAPT (0.57) | MAPTALDH1A1POLBIDO1MAPK1 | |
| SCHEMBL2769872 | 0.75 | MAPT (0.57) | MAPTALDH1A1POLBIDO1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013166466-A1 | HOT-START DIGITAL PCR | BIO-RAD LABORATORIES, INC. (US) | 2013-11-07 | — | — | WO | disclosed |