Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHB4 | P54760 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15603592 | 0.94 | EPHB4 (0.50) | EPHB4HDAC1HDAC8HDAC6BRD4 | |
| SCHEMBL15528912 | 0.90 | EPHB4 (0.41) | EPHB4HDAC1HDAC8HDAC6BRD4 | |
| SCHEMBL15528813 | 0.90 | EPHB4 (0.41) | EPHB4HDAC1HDAC8HDAC6BRD4 | |
| SCHEMBL15603620 | 0.89 | TRPV1 (0.45) | EPHB4HDAC1HDAC8HDAC6BRD4 | |
| SCHEMBL15603565 | 0.88 | CYP11B2 (0.42) | EPHB4HDAC1HDAC8HDAC6BRD4 | |
| SCHEMBL15603595 | 0.84 | HDAC1 (0.44) | EPHB4HDAC1HDAC8HDAC6BRD4 | |
| SCHEMBL15603551 | 0.84 | HDAC1 (0.47) | EPHB4HDAC1HDAC8HDAC6BRD4 | |
| SCHEMBL15603586 | 0.83 | HDAC1 (0.47) | EPHB4HDAC1HDAC8HDAC6BRD4 | |
| SCHEMBL15603583 | 0.83 | HDAC1 (0.50) | HDAC1HDAC8HDAC6BRD4ROCK2 | |
| SCHEMBL15528990 | 0.83 | BRD4 (0.41) | HDAC1HDAC8HDAC6BRD4ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447069-B2 | ROR modulators and their uses | INNOV17 LLC (US) | 2016-09-20 | — | — | US | disclosed |
| US-9447069-B2 | ROR modulators and their uses | INNOV17 LLC (US) | 2016-09-20 | — | — | US | disclosed |
| US-9447069-B2 | ROR modulators and their uses | INNOV17 LLC (US) | 2016-09-20 | — | — | US | disclosed |
| US-20150099779-A1 | ROR MODULATORS AND THEIR USES | INNOV17 LLC | 2015-04-09 | — | — | US | disclosed |
| US-20150099779-A1 | ROR MODULATORS AND THEIR USES | INNOV17 LLC | 2015-04-09 | — | — | US | disclosed |
| US-20150099779-A1 | ROR MODULATORS AND THEIR USES | INNOV17 LLC | 2015-04-09 | — | — | US | disclosed |
| EP-2844260-A1 | ROR MODULATORS AND THEIR USES | Gaweco, Anderson (US) | 2015-03-11 | — | — | EP | disclosed |
| WO-2013166015-A1 | ROR MODULATORS AND THEIR USES | GAWECO ANDERSON (US) | 2013-11-07 | — | — | WO | disclosed |
| WO-2013166015-A1 | ROR MODULATORS AND THEIR USES | GAWECO ANDERSON (US) | 2013-11-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150099779-A1 | ROR MODULATORS AND THEIR USES | RORB, RORA, RORC | EPHB4 425/4885HDAC1 460/4885HDAC8 426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.