Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.53 |
| ▸ | ABL1 | P00519 | 10/20 | 0.47 |
| ▸ | BCR | P11274 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | STAT1 | P42224 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15534267 | 0.83 | TRPV1 (0.56) | SYKABL1BCRMAPTTRPV1 | |
| SCHEMBL15534259 | 0.82 | TRPV1 (0.57) | ABL1BCRTRPV1 | |
| SCHEMBL15533871 | 0.81 | TP53 (0.51) | SYKABL1BCRMEN1MAPT | |
| SCHEMBL1013886 | 0.81 | ABL1 (0.67) | ABL1BCRMEN1KMT2ATRPV1 | |
| SCHEMBL15534464 | 0.81 | ABL1 (0.46) | SYKABL1BCRMAPTTRPV1 | |
| SCHEMBL15533972 | 0.80 | ABL1 (0.53) | SYKABL1BCRMAPTKDM4E | |
| SCHEMBL15534101 | 0.80 | TRPV1 (0.47) | ABL1BCRMEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL15533549 | 0.79 | TRPV1 (0.47) | ABL1BCRMEN1MAPTKMT2A | |
| Bromide SCHEMBL15534396 | 0.79 | TRPV1 (0.47) | ABL1BCRMEN1MAPTKMT2A | |
| SCHEMBL15534503 | 0.79 | ABL1 (0.48) | ABL1BCRMEN1KMT2ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | claimed |
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | disclosed |