Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 13/20 | 0.53 |
| ▸ | BCR | P11274 | 13/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15533969 | 0.91 | CYP1A1 (0.48) | ABL1BCRSYKFAAHTP53 | |
| SCHEMBL15533691 | 0.86 | MAPT (0.47) | ABL1BCRKDM4ETP53MAPT | |
| SCHEMBL15534259 | 0.85 | TRPV1 (0.57) | ABL1BCRFAAH | |
| SCHEMBL15533871 | 0.85 | TP53 (0.51) | ABL1BCRSYKKDM4EFAAH | |
| SCHEMBL15533818 | 0.84 | CYP2D6 (0.50) | SYKADORA3TP53MAPTCCNT1 | |
| SCHEMBL15534464 | 0.84 | ABL1 (0.46) | ABL1BCRSYKTP53MAPT | |
| SCHEMBL15534267 | 0.84 | TRPV1 (0.56) | ABL1BCRSYKFAAHTP53 | |
| SCHEMBL15533746 | 0.81 | SYK (0.48) | ABL1BCRSYKKDM4EFAAH | |
| SCHEMBL15534101 | 0.81 | TRPV1 (0.47) | ABL1BCRKDM4EFAAHTP53 | |
| SCHEMBL15534734 | 0.80 | ABL1 (0.43) | ABL1BCRSYKKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | claimed |
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | disclosed |