Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.77 |
| ▸ | PPARD | Q03181 | 5/20 | 0.77 |
| ▸ | PPARA | Q07869 | 5/20 | 0.77 |
| ▸ | F7 | P08709 | 5/20 | 0.77 |
| ▸ | F3 | P13726 | 5/20 | 0.77 |
| ▸ | TERT | O14746 | 3/20 | 0.77 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.77 |
| ▸ | FABP4 | P15090 | 3/20 | 0.77 |
| ▸ | TOP1 | P11387 | 3/20 | 0.77 |
| ▸ | MAPT | P10636 | 2/20 | 0.77 |
| ▸ | BLM | P54132 | 2/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.77 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.77 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.77 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.77 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.77 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.77 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oleic Acid SCHEMBL28166148 | 1.00 | PPARG (0.77) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL28165912 | 0.97 | PPARG (0.77) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL8881225 | 0.97 | PPARG (0.77) | PPARGPPARDPPARAF7F3 | |
| Sulfuric Acid SCHEMBL23933747 | 0.92 | PPARG (0.79) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL8883826 | 0.92 | PPARG (0.79) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL1080939 | 0.91 | PPARG (0.85) | PPARGPPARDPPARAF7F3 | |
| Erucic Acid SCHEMBL8923003 | 0.91 | PPARG (0.85) | PPARGPPARDPPARAF7F3 | |
| Erucic Acid SCHEMBL8922990 | 0.91 | PPARG (0.85) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL1080934 | 0.91 | PPARG (0.85) | PPARGPPARDPPARAF7F3 | |
| Oleic Acid SCHEMBL28352028 | 0.90 | PPARG (0.77) | PPARGPPARDPPARAF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220175872-A1 | THERMOGENIC COMPOSITIONS AND METHODS | OHIO STATE INNOVATION FOUNDATION | 2022-06-09 | — | — | US | disclosed |
| US-20190083574-A1 | THERMOGENIC COMPOSITIONS AND METHODS | OHIO STATE INNOVATION FOUNDATION (US) | 2019-03-21 | — | — | US | disclosed |
| US-10098967-B2 | Self-assembly of therapeutic agent-peptide nanostructures | OHIO STATE INNOVATION FOUNDATION (US) | 2018-10-16 | — | — | US | disclosed |
| WO-2017172881-A1 | THERMOGENIC COMPOSITIONS AND METHODS | OHIO STATE INNOVATION FOUNDATION (US) | 2017-10-05 | — | — | WO | disclosed |
| EP-2847207-A1 | PREPARATIONS OF HYDROPHOBIC THERAPEUTIC AGENTS, METHODS OF MANUFACTURE AND USE THEREOF | Aciex Therapeutics, Inc. (US) | 2015-03-18 | — | — | EP | disclosed |
| US-20140155577-A1 | SELF-ASSEMBLY OF THERAPEUTIC AGENT-PEPTIDE NANOSTRUCTURES | OHIO STATE INNOVATION FOUNDATION (US) | 2014-06-05 | — | — | US | disclosed |
| WO-2013169647-A1 | PREPARATIONS OF HYDROPHOBIC THERAPEUTIC AGENTS, METHODS OF MANUFACTURE AND USE THEREOF | ACIEX THERAPEUTICS, INC. (US) | 2013-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220175872-A1 | THERMOGENIC COMPOSITIONS AND METHODS | LRBA, IAPP, FABP4 | PPARG 121/4885PPARD 246/4885PPARA 276/4885 |
| US-20140155577-A1 | SELF-ASSEMBLY OF THERAPEUTIC AGENT-PEPTIDE NANOSTRUCTURES | IAPP, TAP1, LNPEP | PPARG 4616/4885PPARD 4648/4885PPARA 3483/4885 |
| US-10098967-B2 | Self-assembly of therapeutic agent-peptide nanostructures | IAPP, NPPA, TAP1 | PPARG 4562/4885PPARD 4567/4885PPARA 3695/4885 |
| US-20190083574-A1 | THERMOGENIC COMPOSITIONS AND METHODS | LRBA, IAPP, FABP4 | PPARG 121/4885PPARD 246/4885PPARA 276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.