Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 7/20 | 0.59 |
| ▸ | BCR | P11274 | 7/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.51 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15534046 | 0.86 | ABL1 (0.68) | ABL1BCRTP53MAPTTRPV1 | |
| SCHEMBL15534053 | 0.83 | ABL1 (0.50) | ABL1BCRTRPV1FAAHGAA | |
| SCHEMBL15533534 | 0.81 | THRB (0.58) | ABL1BCRTHRBTP53MAPT | |
| SCHEMBL1387447 | 0.80 | THRB (0.80) | ABL1BCRTHRBEGFRERBB4 | |
| SCHEMBL15534101 | 0.80 | TRPV1 (0.47) | ABL1BCRTP53MAPTTRPV1 | |
| SCHEMBL15534555 | 0.80 | ABL1 (0.49) | ABL1BCRMAPTTRPV1FAAH | |
| SCHEMBL19420148 | 0.79 | THRB (0.70) | ABL1BCRTHRBMAPTEGFR | |
| SCHEMBL15533974 | 0.79 | ABL1 (0.69) | ABL1BCRTP53MAPTTRPV1 | |
| Hydrochloric Acid SCHEMBL15533549 | 0.79 | TRPV1 (0.47) | ABL1BCRTP53MAPTTRPV1 | |
| Bromide SCHEMBL15534396 | 0.79 | TRPV1 (0.47) | ABL1BCRTP53MAPTTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | claimed |
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | disclosed |