Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CLK1 | P49759 | 3/20 | 0.43 |
| ▸ | CLK2 | P49760 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CTSC | P53634 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15534057 | 0.86 | CLK1 (0.47) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL15534289 | 0.84 | SYK (0.59) | CLK1CLK2DYRK1ACLK4DYRK1B | |
| SCHEMBL15533647 | 0.82 | PIK3CG (0.45) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL15533684 | 0.81 | DYRK1A (0.47) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL15533706 | 0.81 | MEN1 (0.46) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL15534386 | 0.80 | DYRK1A (0.68) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL15534293 | 0.80 | SYK (0.49) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL15533886 | 0.79 | CLK1 (0.67) | CLK1CLK2DYRK1ACLK4DYRK1B | |
| SCHEMBL15534555 | 0.79 | ABL1 (0.49) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL15533252 | 0.77 | DKK1 (0.47) | CLK1CLK2DYRK1ACLK4DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | claimed |
| WO-2013175415-A1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND USES THEREOF | Piramal Enterprises Limited (IN) | 2013-11-28 | — | — | WO | disclosed |