SCHEMBL15534638

SCHEMBL15534638

CCOC(=O)Cc1ccccc1OOC(OC(C)=O)C(=O)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
CYP3A4 P08684 2/20 0.42
TBXAS1 P24557 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.39
PKM P14618 1/20 0.38
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
KMT2A Q03164 1/20 0.36
LMNA P02545 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.35
CYP4F2 P78329 1/20 0.35
CYP4A11 Q02928 1/20 0.35
GAA P10253 1/20 0.35
TSHR P16473 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
CFD P00746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21268099 0.87 ALDH1A1 (0.47) ALDH1A1CYP3A4SMN1; SMN2L3MBTL1CFD
SCHEMBL3175900 0.74 ALDH1A1 (0.43) ALDH1A1CYP3A4SMN1; SMN2MEN1KMT2A
SCHEMBL29188697 0.73 ALDH1A1 (0.58) ALDH1A1CYP3A4SMN1; SMN2MEN1NPC1
SCHEMBL28392981 0.73 TBXAS1 (0.50) ALDH1A1TBXAS1PKMNPC1L3MBTL1
SCHEMBL1152586 0.72 L3MBTL1 (0.45) ALDH1A1CYP3A4SMN1; SMN2L3MBTL1CFD
SCHEMBL156451 0.71 ALDH1A1 (0.65) ALDH1A1CYP3A4MEN1NPC1KMT2A
SCHEMBL28999808 0.70 ALDH1A1 (0.47) ALDH1A1CYP3A4SMN1; SMN2MEN1NPC1
SCHEMBL1978808 0.70 ALDH1A1 (0.47) ALDH1A1CYP3A4SMN1; SMN2KMT2AL3MBTL1
SCHEMBL1792326 0.70 TSHR (0.55) CYP3A4TBXAS1SMN1; SMN2PKMMEN1
SCHEMBL7890168 0.70 TBXAS1 (0.59) ALDH1A1TBXAS1PKMMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2852374-B1 PROCESS FOR DYEING KERATIN FIBRES COMPRISING A DYE/PIGMENT, A PHOTOACTIVE COMPOUND AND A LIGHT SOURCE OREAL (FR) 2019-08-21 EP claimed
US-9730876-B2 Process for dyeing keratin fibres comprising a dye-pigment, a photoactive compound and a light source L'OREAL (FR) 2017-08-15 US claimed
EP-2852374-A1 PROCESS FOR DYEING KERATIN FIBRES COMPRISING A DYE/PIGMENT, A PHOTOACTIVE COMPOUND AND A LIGHT SOURCE L'Oréal (FR) 2015-04-01 EP claimed
WO-2013174871-A1 PROCESS FOR DYEING KERATIN FIBRES COMPRISING A DYE/PIGMENT, A PHOTOACTIVE COMPOUND AND A LIGHT SOURCE L'OREAL (FR) 2013-11-28 WO claimed