Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.47 |
| ▸ | SCD5 | Q86SK9 | 7/20 | 0.42 |
| ▸ | QDPR | P09417 | 2/20 | 0.41 |
| ▸ | SPR | P35270 | 2/20 | 0.40 |
| ▸ | SCD | O00767 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23089202 | 0.85 | PROKR1 (0.49) | PROKR1SCD5SCDHDAC3HDAC4 | |
| SCHEMBL15535562 | 0.82 | GABRP (0.42) | SCD5QDPRSCDLMNAHDAC3 | |
| SCHEMBL23212044 | 0.82 | HDAC4 (0.53) | PROKR1SCD5QDPRSCDLMNA | |
| SCHEMBL14239639 | 0.80 | GPR119 (0.50) | — | |
| SCHEMBL15689645 | 0.79 | RECQL (0.41) | PROKR1IDO1HDAC3HDAC4HDAC7 | |
| SCHEMBL20744468 | 0.79 | — | — | |
| SCHEMBL4846274 | 0.78 | LMNA (0.62) | PROKR1SCD5SPRSCDLMNA | |
| SCHEMBL1856770 | 0.78 | LMNA (0.55) | SCD5SPRSCDLMNAHSD11B1 | |
| SCHEMBL2661814 | 0.76 | EPHX2 (0.44) | SCD5 | |
| SCHEMBL15535084 | 0.75 | PROKR1 (0.43) | PROKR1QDPRSPRLMNAHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2852584-A1 | SUBSTITUTED DIPYRIDYLAMINES AND USES THEREOF | F. Hoffmann-La Roche AG (CH) | 2015-04-01 | — | — | EP | disclosed |
| WO-2013174780-A1 | SUBSTITUTED DIPYRIDYLAMINES AND USES THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2013-11-28 | — | — | WO | disclosed |