SCHEMBL4420726

SCHEMBL4420726

C=CCc1cc(C)cc(O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
XDH P47989 1/20 0.44
GABRA1 P14867 4/20 0.42
GABRB2 P47870 4/20 0.42
GAA P10253 3/20 0.42
PPARG P37231 2/20 0.42
PPARD Q03181 2/20 0.42
MEN1 O00255 2/20 0.42
MAPT P10636 2/20 0.42
CNR1 P21554 2/20 0.42
CNR2 P34972 2/20 0.42
KMT2A Q03164 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH2 P05091 1/20 0.42
AKR1B1 P15121 1/20 0.42
HPGD P15428 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ALOX5 P09917 3/20 0.41
CYP3A4 P08684 2/20 0.41
AR P10275 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4465266 0.84 XDH (0.52) ALDH1A1XDHGABRA1GABRB2GAA
SCHEMBL1553874 0.84 ALDH1A1 (0.42) ALDH1A1XDHGABRA1GABRB2GAA
SCHEMBL1514254 0.84 XDH (0.52) ALDH1A1XDHGABRA1GABRB2GAA
Chavicol SCHEMBL20945346 0.82 XDH (0.48) ALDH1A1XDHGABRA1GABRB2GAA
SCHEMBL13224699 0.81 ALDH1A1 (0.50) ALDH1A1MEN1MAPTKMT2AAKR1B1
SCHEMBL23854327 0.79 XDH (0.44) ALDH1A1XDHGABRA1GABRB2GAA
SCHEMBL29859896 0.79 XDH (0.44) ALDH1A1XDHGABRA1GABRB2GAA
SCHEMBL14401171 0.77 ACHE (0.58) ALDH1A1XDHGABRA1GABRB2GAA
Metacresol SCHEMBL11073151 0.76 ACHE (0.59) ALDH1A1XDHGABRA1GABRB2GAA
SCHEMBL16950585 0.75 TACR1 (0.37) ALDH1A1XDHGABRA1GABRB2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1526169-B1 LUBRICATING OIL COMPOSITION NIPPON OIL CORP (JP) 2013-04-10 EP disclosed
US-7625847-B2 Comprises calcium salicylate and phosphorus compounds; improved anti-wear properties and long drain properties; for internal combustion engines NIPPON OIL CORPORATION (JP) 2009-12-01 US disclosed
CN-100558868-C Lubricating oil composition NIPPON OIL CORP (JP) 2009-11-11 CN disclosed
US-7612025-B2 Lubricating oil composition NIPPON OIL CORPORATION (JP) 2009-11-03 US disclosed
US-7563752-B2 Lubricating oil compositions NIPPON OIL CORPORATION (JP) 2009-07-21 US disclosed
CN-100500818-C Lubricating oil compositions NIPPON OIL CORP (JP) 2009-06-17 CN disclosed
CN-100462424-C Lubricating oil compositions NIPPON OIL CORP (JP) 2009-02-18 CN disclosed
CN-1926225-A Lubricating oil composition NIPPON OIL CORP (JP) 2007-03-07 CN disclosed
US-20060270567-A1 Lubricating Oil Composition NIPPON OIL CORPORATION (JP) 2006-11-30 US disclosed
EP-1712606-A1 LUBRICATING OIL COMPOSITION Nippon Oil Corporation (JP) 2006-10-18 EP disclosed
CN-1681909-A Lubricating oil composition NIPPON OIL CORP (JP) 2005-10-12 CN disclosed
CN-1681910-A Lubricating oil compositions NIPPON OIL CORP (JP) 2005-10-12 CN disclosed
US-20050130855-A1 Lubricating oil compositions NIPPON OIL CORPORATION 2005-06-16 US disclosed
US-20050130854-A1 Comprises calcium salicylate and phosphorus compounds; improved anti-wear properties and long drain properties; for internal combustion engines NIPPON OIL CORPORATION 2005-06-16 US disclosed
EP-1526170-A1 LUBRICATING OIL COMPOSITION Nippon Oil Corporation (JP) 2005-04-27 EP disclosed
EP-1526169-A1 LUBRICATING OIL COMPOSITION Nippon Oil Corporation (JP) 2005-04-27 EP disclosed
EP-0370343-B1 METHOD FOR THE PRODUCTION OF 4-METHYL-2-CYCLOHEXYLPHENOL BAYER AG (DE) 1993-02-03 EP disclosed
US-4990687-A Preparation of 4-methyl-2-cyclohexylphenol BAYER AKTIENGESELLSCHAFT (DE) 1991-02-05 US disclosed
EP-0370343-A1 Method for the production of 4-methyl-2-cyclohexylphenol BAYER AG (DE) 1990-05-30 EP disclosed
US-3992455-A CHEMICAL INTERMEDIATES FOR INSECTICIDES KOPPERS COMPANY, INC. (US) 1976-11-16 US disclosed