Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 7/20 | 0.37 |
| ▸ | GSK3B | P49841 | 4/20 | 0.36 |
| ▸ | HPGDS | O60760 | 4/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | WNT1 | P04628 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15539973 | 1.00 | LIPE (0.37) | LIPEDYRK1AGSK3BHPGDSMTOR | |
| SCHEMBL15539677 | 0.98 | DYRK1A (0.37) | LIPEDYRK1AGSK3BHPGDSMTOR | |
| SCHEMBL15538527 | 0.91 | LIPE (0.39) | LIPEDYRK1AGSK3BHPGDSWNT1 | |
| SCHEMBL15538832 | 0.90 | HPGDS (0.37) | LIPEHPGDSMTORSCN9ASCN3A | |
| SCHEMBL15539956 | 0.89 | GPR119 (0.45) | DYRK1AGSK3BHPGDSGPR119 | |
| SCHEMBL15538345 | 0.89 | GPR119 (0.35) | LIPEDYRK1AGSK3BHPGDSWNT1 | |
| SCHEMBL15539246 | 0.88 | DYRK1A (0.39) | LIPEDYRK1AGSK3BHPGDSWNT1 | |
| SCHEMBL15537815 | 0.87 | GPR119 (0.45) | DYRK1AGSK3BHPGDSGPR119 | |
| SCHEMBL15538470 | 0.87 | SCN9A (0.36) | DYRK1AGSK3BHPGDSWNT1GPR119 | |
| SCHEMBL15538132 | 0.87 | GPR119 (0.39) | DYRK1AGSK3BHPGDSWNT1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | Chong Kun Dang Pharmaceutical Corp. (KR) | 2015-04-15 | — | — | EP | disclosed |
| WO-2013187646-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2013-12-19 | — | — | WO | disclosed |