Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 7/20 | 0.39 |
| ▸ | WNT1 | P04628 | 3/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 3/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 3/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15538527 | 0.98 | LIPE (0.39) | DYRK1AWNT1LIPEACHEHPGDS | |
| SCHEMBL15539034 | 0.94 | LIPE (0.37) | DYRK1AWNT1LIPEACHEHPGDS | |
| SCHEMBL15539677 | 0.91 | DYRK1A (0.37) | DYRK1AWNT1LIPEHPGDSGSK3B | |
| SCHEMBL15538470 | 0.89 | SCN9A (0.36) | DYRK1AWNT1ACHEHPGDSGSK3B | |
| SCHEMBL15539766 | 0.89 | WDR5 (0.38) | DYRK1AWNT1LIPEGSK3B | |
| SCHEMBL15538813 | 0.89 | WDR5 (0.38) | DYRK1AWNT1LIPEGSK3B | |
| SCHEMBL15539503 | 0.89 | DYRK1A (0.41) | DYRK1AWNT1GSK3BCTSSATM | |
| SCHEMBL15539973 | 0.88 | LIPE (0.37) | DYRK1AWNT1LIPEHPGDSGSK3B | |
| SCHEMBL15538893 | 0.88 | LIPE (0.37) | DYRK1AWNT1LIPEHPGDSGSK3B | |
| SCHEMBL15539527 | 0.87 | WNT1 (0.38) | DYRK1AWNT1LIPEACHEGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | Chong Kun Dang Pharmaceutical Corp. (KR) | 2015-04-15 | — | — | EP | claimed |
| WO-2013187646-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2013-12-19 | — | — | WO | claimed |
| EP-2858986-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | Chong Kun Dang Pharmaceutical Corp. (KR) | 2015-04-15 | — | — | EP | disclosed |
| WO-2013187646-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2013-12-19 | — | — | WO | disclosed |