Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 8/20 | 0.41 |
| ▸ | WNT1 | P04628 | 3/20 | 0.41 |
| ▸ | WDR5 | P61964 | 6/20 | 0.39 |
| ▸ | GSK3B | P49841 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15539990 | 0.98 | DYRK1A (0.41) | DYRK1AWNT1WDR5GSK3BHTR2A | |
| SCHEMBL15538993 | 0.98 | DYRK1A (0.41) | DYRK1AWNT1WDR5GSK3BHTR2A | |
| SCHEMBL16757945 | 0.93 | WDR5 (0.38) | DYRK1AWNT1WDR5GSK3BHTR2A | |
| SCHEMBL15538132 | 0.91 | GPR119 (0.39) | DYRK1AWNT1WDR5GSK3BHTR2A | |
| SCHEMBL15539060 | 0.90 | GPR119 (0.37) | DYRK1AWNT1WDR5GSK3BHTR2A | |
| SCHEMBL15538114 | 0.89 | DYRK1A (0.43) | DYRK1AWNT1WDR5GSK3BCHRM4 | |
| SCHEMBL15539246 | 0.89 | DYRK1A (0.39) | DYRK1AWNT1GSK3BATMCTSS | |
| SCHEMBL15539537 | 0.88 | GPR119 (0.39) | DYRK1AWNT1GSK3BHTR2AHTR2C | |
| SCHEMBL15538222 | 0.87 | WNT1 (0.38) | DYRK1AWNT1WDR5GSK3BHTR2A | |
| SCHEMBL15538931 | 0.87 | GPR119 (0.49) | DYRK1AWNT1GSK3BHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | Chong Kun Dang Pharmaceutical Corp. (KR) | 2015-04-15 | — | — | EP | claimed |
| WO-2013187646-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2013-12-19 | — | — | WO | claimed |
| EP-2858986-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | Chong Kun Dang Pharmaceutical Corp. (KR) | 2015-04-15 | — | — | EP | disclosed |
| WO-2013187646-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2013-12-19 | — | — | WO | disclosed |