SCHEMBL15539558

SCHEMBL15539558

CC(C)(F)CN1CCC(COc2ccc(-c3ccc(C(=O)O)cc3)c(F)c2)CC1

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SSTR5 P35346 3/20 0.51
KCNH2 Q12809 1/20 0.51
FFAR4 Q5NUL3 2/20 0.43
PARP10 Q53GL7 2/20 0.40
PARP15 Q460N3 1/20 0.40
RBP4 P02753 1/20 0.39
TTR P02766 1/20 0.39
P2RY1 P47900 1/20 0.39
SCN9A Q15858 1/20 0.39
SRD5A2 P31213 1/20 0.39
S1PR1 P21453 1/20 0.39
S1PR3 Q99500 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15539248 0.94 SSTR5 (0.51) SSTR5KCNH2FFAR4RBP4TTR
SCHEMBL15538718 0.92 SSTR5 (0.46) SSTR5KCNH2PARP10PARP15RBP4
SCHEMBL16758044 0.91 SSTR5 (0.51) SSTR5KCNH2FFAR4PARP10PARP15
SCHEMBL15539071 0.91 EGFR (0.42) SSTR5KCNH2FFAR4PARP10PARP15
SCHEMBL20053739 0.89 ADRB2 (0.45) SSTR5KCNH2
SCHEMBL15537819 0.89 PARP10 (0.45) SSTR5KCNH2FFAR4PARP10PARP15
SCHEMBL15539951 0.88 SSTR5 (0.47) SSTR5KCNH2
SCHEMBL15539809 0.88 KCNH2 (0.41) SSTR5KCNH2FFAR4PARP10PARP15
SCHEMBL15537615 0.88 SSTR5 (0.55) SSTR5KCNH2PARP10PARP15SRD5A2
SCHEMBL15539452 0.87 SSTR5 (0.43) SSTR5KCNH2FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2858986-B1 PIPERIDINE DERIVATIVES AS GPR119 AGONISTS CHONG KUN DANG PHARMACEUTICAL CORP (KR) 2019-10-30 EP disclosed
US-9944600-B2 Piperidine derivatives for GPR119 agonist CHONG KUN DANG PHARMACEUTICAL CORP. (KR) 2018-04-17 US disclosed
US-20150166480-A1 PIPERIDINE DERIVATIVES FOR GPR119 AGONIST CHONG KUN DANG PHARMACEUTICAL CORP. (KR) 2015-06-18 US disclosed
EP-2858986-A1 PIPERIDINE DERIVATIVES FOR GPR119 AGONIST Chong Kun Dang Pharmaceutical Corp. (KR) 2015-04-15 EP disclosed
WO-2013187646-A1 PIPERIDINE DERIVATIVES FOR GPR119 AGONIST CHONG KUN DANG PHARMACEUTICAL CORP. (KR) 2013-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150166480-A1 PIPERIDINE DERIVATIVES FOR GPR119 AGONIST GPR119, FFAR2, GPR84 SSTR5 104/4885KCNH2 680/4885FFAR4 21/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.