Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 6/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | WNT1 | P04628 | 1/20 | 0.38 |
| ▸ | IKBKE | Q14164 | 7/20 | 0.38 |
| ▸ | TBK1 | Q9UHD2 | 7/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15539377 | 0.91 | HTR2A (0.41) | CTSSDYRK1AWNT1 | |
| SCHEMBL15539544 | 0.86 | XDH (0.36) | XDHDYRK1AWNT1IKBKETBK1 | |
| SCHEMBL15539794 | 0.84 | HTR2A (0.37) | XDHCTSSDYRK1AWNT1IKBKE | |
| SCHEMBL15537941 | 0.83 | XDH (0.44) | XDHDYRK1AWNT1IKBKETBK1 | |
| SCHEMBL15539155 | 0.83 | XDH (0.50) | XDHIKBKETBK1 | |
| SCHEMBL15539086 | 0.83 | DYRK1A (0.38) | CTSSDYRK1AWNT1KCNH2 | |
| SCHEMBL15538251 | 0.82 | CTSK (0.38) | XDHDYRK1AWNT1IKBKETBK1 | |
| SCHEMBL20053637 | 0.82 | XDH (0.45) | XDHCTSSIKBKETBK1 | |
| SCHEMBL15538267 | 0.80 | DYRK1A (0.37) | CTSSDYRK1AWNT1 | |
| SCHEMBL15539246 | 0.79 | DYRK1A (0.39) | CTSSDYRK1AWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | Chong Kun Dang Pharmaceutical Corp. (KR) | 2015-04-15 | — | — | EP | claimed |
| WO-2013187646-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2013-12-19 | — | — | WO | claimed |
| EP-2858986-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | Chong Kun Dang Pharmaceutical Corp. (KR) | 2015-04-15 | — | — | EP | disclosed |
| WO-2013187646-A1 | PIPERIDINE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2013-12-19 | — | — | WO | disclosed |