Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1553047 | 0.84 | LDHA (0.45) | MAPK1ABL1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL1553979 | 0.81 | — | — | |
| SCHEMBL1553394 | 0.71 | CYP2C9 (0.46) | GAAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL29598250 | 0.70 | MAPK1 (0.61) | MAPK1HPGDSMAPTSMN1; SMN2KDM4E | |
| SCHEMBL1553290 | 0.70 | ABL1 (0.54) | MAPK1ABL1PIM1AURKB | |
| SCHEMBL4909766 | 0.70 | GAA (0.42) | GAAABL1MAPTKDM4E | |
| SCHEMBL29651074 | 0.70 | MAPK1 (0.69) | MAPK1HPGDSMAPTKDM4EL3MBTL1 | |
| SCHEMBL29651058 | 0.70 | MAPK1 (0.69) | MAPK1HPGDSMAPTKDM4EL3MBTL1 | |
| SCHEMBL70712 | 0.70 | MAPK1 (0.69) | MAPK1HPGDSMAPTKDM4EL3MBTL1 | |
| SCHEMBL1553044 | 0.69 | HCAR3 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102199-B1 | ANTIBACTERIAL POLYCYCLIC UREA COMPOUNDS | ASTRAZENECA AB (SE) | 2011-04-27 | — | — | EP | disclosed |