Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.32 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6187047 | 0.81 | EPHX1 (0.46) | CHRM3SIGMAR1DPP4DPP7CHRNB2 | |
| SCHEMBL1022186 | 0.80 | CHRNB2 (0.34) | SIGMAR1DPP4DPP7CHRNB2CHRNA3 | |
| SCHEMBL1022188 | 0.80 | CHRNB2 (0.34) | SIGMAR1DPP4DPP7CHRNB2CHRNA3 | |
| SCHEMBL1555261 | 0.78 | SIGMAR1 (0.35) | CHRM3SIGMAR1CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL1554232 | 0.75 | CYP2D6 (0.37) | SIGMAR1CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL1553591 | 0.75 | SIGMAR1 (0.39) | SIGMAR1CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL1555130 | 0.75 | CYP2D6 (0.37) | SIGMAR1CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL6585188 | 0.73 | CPN1 (0.34) | DPP4CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL25380666 | 0.71 | CHRNB2 (0.41) | CHRM3SIGMAR1CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL978921 | 0.69 | HSD11B1 (0.31) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011000945-A9 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-04-07 | — | — | WO | claimed |