Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 6/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15540240 | 0.89 | HPGDS (0.48) | HPGDSCYP2A6CYP19A1KDM4ESMN1; SMN2 | |
| SCHEMBL15539855 | 0.83 | HPGDS (0.48) | HPGDSCYP2A6CYP19A1KDM4ESMN1; SMN2 | |
| SCHEMBL15540850 | 0.82 | CYP2A6 (0.50) | HPGDSCYP2A6CYP19A1HSD17B10KDM4E | |
| SCHEMBL8403765 | 0.80 | HPGDS (0.50) | HPGDSCYP2A6CYP19A1KDM4ESMN1; SMN2 | |
| SCHEMBL15540975 | 0.79 | HPGDS (0.48) | HPGDSCYP2A6CYP19A1HSD17B10KDM4E | |
| SCHEMBL15540036 | 0.78 | CYP2A6 (0.56) | HPGDSCYP2A6CYP19A1HSD17B10KDM4E | |
| SCHEMBL12279413 | 0.73 | HPGDS (0.71) | HPGDSCYP2A6CYP19A1KDM4ESMN1; SMN2 | |
| SCHEMBL12278703 | 0.72 | KDM4E (0.66) | CYP2A6CYP19A1HSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL16601901 | 0.70 | KDM4E (0.59) | HPGDSCYP2A6CYP19A1HSD17B10KDM4E | |
| SCHEMBL2820252 | 0.70 | HPGDS (0.54) | HPGDSCYP2A6CYP19A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150166528-A1 | Pesticidal methods using substituted 3-pyridyl thiazole compounds and derivatives for combating animal pests | BASF SE (DE) | 2015-06-18 | — | — | US | disclosed |
| US-20150166528-A1 | Pesticidal methods using substituted 3-pyridyl thiazole compounds and derivatives for combating animal pests | BASF SE (DE) | 2015-06-18 | — | — | US | disclosed |
| US-20150166528-A1 | Pesticidal methods using substituted 3-pyridyl thiazole compounds and derivatives for combating animal pests | BASF SE (DE) | 2015-06-18 | — | — | US | disclosed |
| EP-2863738-A2 | PESTICIDAL METHODS USING SUBSTITUTED 3-PYRIDYL THIAZOLE COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2015-04-29 | — | — | EP | disclosed |
| WO-2013186089-A2 | PESTICIDAL METHODS USING SUBSTITUTED 3-PYRIDYL THIAZOLE COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2013-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166528-A1 | Pesticidal methods using substituted 3-pyridyl thiazole compounds and derivatives for combating animal pests | PTMS, PDXK, TH | HPGDS 2618/4885CYP2A6 1875/4885CYP19A1 3178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.