Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15539855 | 0.84 | HPGDS (0.48) | HPGDSRAB9ANPC1CYP2A6ALOX5 | |
| SCHEMBL15540240 | 0.81 | HPGDS (0.48) | HPGDSRAB9ANPC1CYP2A6ALOX5 | |
| SCHEMBL15540239 | 0.79 | HPGDS (0.47) | HPGDSRAB9ANPC1CYP2A6ALOX5 | |
| SCHEMBL8403765 | 0.77 | HPGDS (0.50) | HPGDSRAB9ANPC1CYP2A6ALOX5 | |
| SCHEMBL15540850 | 0.77 | CYP2A6 (0.50) | HPGDSRAB9ANPC1CYP2A6KDM4E | |
| SCHEMBL15540942 | 0.77 | RAB9A (0.46) | HPGDSRAB9ANPC1CYP2A6ALOX5 | |
| SCHEMBL15540462 | 0.77 | RAB9A (0.46) | HPGDSRAB9ANPC1CYP2A6ALOX5 | |
| SCHEMBL15540036 | 0.76 | CYP2A6 (0.56) | HPGDSRAB9ANPC1CYP2A6KDM4E | |
| SCHEMBL9100796 | 0.73 | EHMT2 (0.45) | RAB9ANPC1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL211069 | 0.72 | EHMT2 (0.44) | RAB9ANPC1KDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150166528-A1 | Pesticidal methods using substituted 3-pyridyl thiazole compounds and derivatives for combating animal pests | BASF SE (DE) | 2015-06-18 | — | — | US | disclosed |
| US-20150166528-A1 | Pesticidal methods using substituted 3-pyridyl thiazole compounds and derivatives for combating animal pests | BASF SE (DE) | 2015-06-18 | — | — | US | disclosed |
| US-20150166528-A1 | Pesticidal methods using substituted 3-pyridyl thiazole compounds and derivatives for combating animal pests | BASF SE (DE) | 2015-06-18 | — | — | US | disclosed |
| EP-2863738-A2 | PESTICIDAL METHODS USING SUBSTITUTED 3-PYRIDYL THIAZOLE COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2015-04-29 | — | — | EP | disclosed |
| WO-2013186089-A2 | PESTICIDAL METHODS USING SUBSTITUTED 3-PYRIDYL THIAZOLE COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS | BASF SE (DE) | 2013-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150166528-A1 | Pesticidal methods using substituted 3-pyridyl thiazole compounds and derivatives for combating animal pests | PTMS, PDXK, TH | HPGDS 2618/4885RAB9A 2053/4885NPC1 3705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.