Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | BACE1 | P56817 | 6/20 | 0.52 |
| ▸ | SNCA | P37840 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | APEX1 | P27695 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | CNR1 | P21554 | 2/20 | 0.52 |
| ▸ | RAD52 | P43351 | 2/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.46 |
| ▸ | APP | P05067 | 3/20 | 0.46 |
| ▸ | MET | P08581 | 2/20 | 0.46 |
| ▸ | BCL2 | P10415 | 2/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28616927 | 0.91 | RECQL (0.44) | RECQLTDP1BACE1SNCAKDM4E | |
| SCHEMBL8249167 | 0.86 | KDM4E (0.54) | RECQLTDP1BACE1SNCAKDM4E | |
| SCHEMBL2781922 | 0.86 | KDM4E (0.54) | RECQLTDP1BACE1SNCAKDM4E | |
| SCHEMBL16151244 | 0.86 | KDM4E (0.54) | RECQLTDP1BACE1SNCAKDM4E | |
| SCHEMBL349722 | 0.85 | CYP3A4 (0.52) | RECQLTDP1BACE1SNCAKDM4E | |
| SCHEMBL3487578 | 0.85 | CYP3A4 (0.52) | RECQLTDP1BACE1SNCAKDM4E | |
| SCHEMBL1508796 | 0.84 | MEN1 (0.49) | RECQLTDP1BACE1SNCAKDM4E | |
| SCHEMBL7809366 | 0.82 | CYP19A1 (0.45) | RECQLTDP1BACE1SNCAKDM4E | |
| SCHEMBL29282180 | 0.82 | CYP19A1 (0.45) | RECQLTDP1BACE1SNCAKDM4E | |
| SCHEMBL2319151 | 0.80 | CYP19A1 (0.57) | MAPTALDH1A1HPGDHSD17B10PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240263203-A1 | RECOMBINANT HOST CELLS WITH IMPROVED PRODUCTION OF TETRAKETIDE DERIVATIVES | IPTECTOR ASSETS APS (DK) | 2024-08-08 | — | — | US | disclosed |
| US-20220257561-A1 | COMPOSITIONS AND METHODS FOR IMPROVING WELLNESS | ADVANCED DELIVERY LABS LLC (US) | 2022-08-18 | — | — | US | disclosed |
| EP-3906301-A1 | RECOMBINANT HOST CELLS WITH IMPROVED PRODUCTION OF TETRAKETIDE DERIVATIVES | Barrit Sarl (FR) | 2021-11-10 | — | — | EP | disclosed |
| WO-2020141230-A1 | RECOMBINANT HOST CELLS WITH IMPROVED PRODUCTION OF TETRAKETIDE DERIVATIVES | BARRIT SARL (FR) | 2020-07-09 | — | — | WO | disclosed |
| WO-2014007853-A1 | DIHYDROMYRICETIN FOR THE TREATMENT OF DISEASES AND DISORDERS OF THE GLUTAMATERGIC SYSTEM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-01-09 | — | — | WO | disclosed |