SCHEMBL15544743

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13746013	0.79	NCF1 (0.42)	NOS2NOS3NOS1NCF1MCHR1
	SCHEMBL359862	0.77	MCHR1 (0.50)	NOS2NOS3NOS1NCF1MCHR1
	SCHEMBL15195554	0.77	CRHBP (0.42)	NOS2NOS3NOS1LMNAGAA
	SCHEMBL10075373	0.76	APOBEC3A (0.42)	KDM4ENPC1LMNARAB9ATP53
	SCHEMBL31253174	0.76	MCHR1 (0.40)	NOS2NOS3NOS1NCF1MCHR1
	SCHEMBL6690974	0.76	CRHBP (0.41)	NOS2NOS3NOS1NCF1MCHR1
	SCHEMBL30531704	0.76	CRHBP (0.41)	NOS2NOS3NOS1NCF1MCHR1
	SCHEMBL20679536	0.76	NCF1 (0.40)	NOS2NOS3NOS1NCF1MCHR1
	SCHEMBL1256181	0.76	MCHR1 (0.40)	NOS2NOS3NOS1NCF1MCHR1
	SCHEMBL1911864	0.74	POLB (0.52)	NPC1RAB9ATSHRHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.