Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 3/20 | 0.62 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | XIAP | P98170 | 1/20 | 0.56 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | FCER2 | P06734 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31614353 | 1.00 | TPH1 (0.62) | TPH1SLC7A5PKMPTGS1ALPI | |
| SCHEMBL30969128 | 1.00 | TPH1 (0.62) | TPH1SLC7A5PKMPTGS1ALPI | |
| SCHEMBL287095 | 1.00 | TPH1 (0.62) | TPH1SLC7A5PKMPTGS1ALPI | |
| SCHEMBL8208523 | 1.00 | TPH1 (0.62) | TPH1SLC7A5PKMPTGS1ALPI | |
| SCHEMBL25420969 | 0.91 | TPH1 (0.55) | TPH1SLC7A5PKMPTGS1ALPI | |
| SCHEMBL27616585 | 0.85 | TPH1 (0.62) | TPH1SLC7A5PKMPTGS1ALPI | |
| SCHEMBL9727511 | 0.83 | TPH1 (0.50) | TPH1RAB9AHSD17B10MMP1FCER2 | |
| SCHEMBL8298247 | 0.83 | TPH1 (0.50) | TPH1RAB9AHSD17B10MMP1FCER2 | |
| SCHEMBL8884067 | 0.83 | SLC7A5 (0.54) | TPH1SLC7A5PKMPTGS1ALPI | |
| SCHEMBL8884063 | 0.83 | SLC7A5 (0.54) | TPH1SLC7A5PKMPTGS1ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 243 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025094171-A1 | SUPERHYDROPHOBIC COATING | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2025-05-08 | — | — | WO | claimed |
| US-20240247034-A1 | CYSTINE KNOT SCAFFOLD PLATFORM | GENENTECH INC (US) | 2024-07-25 | — | — | US | claimed |
| EP-4401555-A1 | ANTIMICROBIAL PEPTIDES | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) | 2024-07-24 | — | — | EP | claimed |
| US-20230174596-A1 | CYSTINE KNOT SCAFFOLD PLATFORM | GENENTECH INC (US) | 2023-06-08 | — | — | US | claimed |
| WO-2023042201-A1 | ANTIMICROBIAL PEPTIDES | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2023-03-23 | — | — | WO | claimed |
| CN-114805487-A | Polypeptide compound and application thereof | 成都诺和晟泰生物科技有限公司 | 2022-07-29 | — | — | CN | claimed |
| CN-114805528-A | Cystine knot scaffold platform | 豪夫迈·罗氏有限公司 | 2022-07-29 | — | — | CN | claimed |
| CN-114591422-A | Cystine knot scaffold platform | 豪夫迈·罗氏有限公司 | 2022-06-07 | — | — | CN | claimed |
| CN-105143245-B | Anti-scaling material | 耶路撒冷希伯来大学伊森姆研究发展有限公司 | 2021-02-05 | — | — | CN | claimed |
| US-20200325187-A1 | CYSTINE KNOT SCAFFOLD PLATFORM | GENENTECH, INC. (US) | 2020-10-15 | — | — | US | claimed |
| EP-3374520-A1 | BIOSENSORS | Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. (IL) | 2018-09-19 | — | — | EP | claimed |
| EP-3350215-A1 | CYSTINE KNOT SCAFFOLD PLATFORM | H. Hoffnabb-La Roche Ag (CH) | 2018-07-25 | — | — | EP | claimed |
| CN-108026162-A | Cystine knot scaffold platform | 豪夫迈·罗氏有限公司 | 2018-05-11 | — | — | CN | claimed |
| WO-2017081684-A1 | BIOSENSORS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) | 2017-05-18 | — | — | WO | claimed |
| US-20170129927-A1 | CYSTINE KNOT SCAFFOLD PLATFORM | GENENTECH INC (US) | 2017-05-11 | — | — | US | claimed |
| US-9631100-B2 | Antifouling materials | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2017-04-25 | — | — | US | claimed |
| WO-2017049009-A1 | CYSTINE KNOT SCAFFOLD PLATFORM | GENENTECH, INC. (US) | 2017-03-23 | — | — | WO | claimed |
| US-20150368480-A1 | ANTIFOULING MATERIALS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) | 2015-12-24 | — | — | US | claimed |
| EP-2951195-A1 | ANTIFOULING MATERIALS | Yissum Research Development Company of The Hebrew University of Jerusalem Ltd. (IL) | 2015-12-09 | — | — | EP | claimed |
| WO-2014118779-A1 | ANTIFOULING MATERIALS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2014-08-07 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240247034-A1 | CYSTINE KNOT SCAFFOLD PLATFORM | LRP6, LDLR, KDR | TPH1 3561/4885SLC7A5 504/4885PKM 603/4885 |
| US-20150368480-A1 | ANTIFOULING MATERIALS | PFAS, FLNB, FLNA | TPH1 3891/4885SLC7A5 2272/4885PKM 3572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.