Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.54 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | TPH1 | P17752 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8884067 | 1.00 | SLC7A5 (0.54) | SLC7A5GRIA2PKMTPH1HSD17B10 | |
| SCHEMBL31614353 | 0.83 | TPH1 (0.62) | SLC7A5PKMTPH1HSD17B10PTGS1 | |
| SCHEMBL287095 | 0.83 | TPH1 (0.62) | SLC7A5PKMTPH1HSD17B10PTGS1 | |
| SCHEMBL8208523 | 0.83 | TPH1 (0.62) | SLC7A5PKMTPH1HSD17B10PTGS1 | |
| SCHEMBL287073 | 0.83 | TPH1 (0.62) | SLC7A5PKMTPH1HSD17B10PTGS1 | |
| SCHEMBL30969128 | 0.83 | TPH1 (0.62) | SLC7A5PKMTPH1HSD17B10PTGS1 | |
| SCHEMBL8883784 | 0.82 | ALDH1A1 (0.56) | PKMTPH1PTGS1KDM4EALDH1A1 | |
| SCHEMBL8883782 | 0.82 | ALDH1A1 (0.56) | PKMTPH1PTGS1KDM4EALDH1A1 | |
| SCHEMBL31091507 | 0.79 | SLC7A5 (0.69) | SLC7A5GRIA2PKMHSD17B10PTGS1 | |
| SCHEMBL15314366 | 0.78 | TPH1 (0.47) | SLC7A5PKMTPH1HSD17B10PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639885-A | Redox amino acids and peptides containing them | UNIVERSITY OF FLORIDA (US) | 1997-06-17 | — | — | US | disclosed |
| EP-0293071-B1 | REDOX AMINO ACIDS AND PEPTIDES CONTAINING THEM | UNIVERSITY OF FLORIDA (US) | 1993-09-01 | — | — | EP | disclosed |
| US-5079366-A | To derivatize pharmaceutical peptides for transport across the blood/brain barrier | UNIVERSITY OF FLORIDA (US) | 1992-01-07 | — | — | US | disclosed |
| US-4888427-A | DIHYDROPYRIDINE-PYRIDINIUM SALT REDOX SYSTEM | UNIVERSITY OF FLORIDA (US) | 1989-12-19 | — | — | US | disclosed |
| EP-0293071-A1 | Redox amino acids and peptides containing them | UNIVERSITY OF FLORIDA (US) | 1988-11-30 | — | — | EP | disclosed |