Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1556668 | 0.72 | KMT2A (0.39) | LMNAKDM4EGAASMN1; SMN2HTT | |
| SCHEMBL1555200 | 0.71 | KMT2A (0.35) | POLBRAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL7977917 | 0.70 | KMT2A (0.41) | PKMKMT2AMAPTALDH1A1TDP1 | |
| SCHEMBL15233 | 0.69 | CES2 (1.00) | CES2CES1PTPN1POLBRAB9A | |
| SCHEMBL2155972 | 0.69 | CES2 (1.00) | CES2CES1PTPN1POLBRAB9A | |
| SCHEMBL30368283 | 0.69 | KMT2A (0.40) | KMT2A | |
| SCHEMBL1555816 | 0.69 | CES2 (0.51) | CES2CES1PTPN1POLBRAB9A | |
| SCHEMBL11606024 | 0.68 | CES2 (0.71) | CES2CES1PTPN1POLBRAB9A | |
| SCHEMBL11448058 | 0.67 | CES2 (0.95) | CES2CES1PTPN1POLBRAB9A | |
| SCHEMBL8199604 | 0.67 | CES2 (0.95) | CES2CES1PTPN1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488533-A1 | IMIDAZOTHIAZOLE-CHALCONE DERIVATIVES AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | Council of Scientific & Industrial Research (IN) | 2012-08-22 | — | — | EP | claimed |
| WO-2011045646-A1 | IMIDAZOTHIAZOLE-CHALCONE DERIVATIVES AS POTENTIAL ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2011-04-21 | — | — | WO | claimed |